Signalling within and between cells is an essential part of many biological processes, from the development of the body, to the activity of our immune system. Recent advances in molecular cell biology have allowed us to identify the components of signalling pathways, and examine how they interact to form the carefully orchestrated and controlled networks upon which the complexity of a living organism is built.Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms.Cell Signalling presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems. · A focus on generic components of extra- and intracellular signalling pathways allows the student to gain a thorough understanding of the underlying principles of cell signalling before exploring how the individual components interact to form complex signalling pathways· The ubiquity of key signalling mechanisms is highlighted, enabling students to see how similar mechanisms are conserved and harnessed in many different biological systems· The student is directed to carefully chosen further reading articles, allowing them to readily explore key topics in more detailOnline Resource Centre The Online Resource Centre to accompany Cell Signalling features:For students:· Links to useful websites· Hyperlinked referencesFor Lecturers:· All figures from the book
Complexity and specificity are the hallmarks of cell signalling, yet Hancock in this third edition has gone a long way to simplify these complicated processes. His signalling examples are clever and well-conceived, his writing descriptive and his passion for his subject infectious ... this is marvellous value for money and is a worthy companion to an undergraduate/postgraduate reference libary. John P. Phelan, Waterford Institute of Technology, Ireland in The Biochemist
Dr John Hancock, Reader in Molecular Biology, Faculty of Applied Science, University of the West of England, Bristol, UK.