Decoding the Genomic Control of Immune Reactions
Fr. 150.00
inkl. MwStBeschreibung
Details
Format
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
04.04.2007
Herausgeber
Gregory R. Bock + weiteregenome sequences of human, mouse, other vertebrates and human
pathogens to solve key problems in the treatment of immunological
diseases and chronic infections. The assembled genome
sequences now provide important opportunities for solving these
problems, but a major bottleneck is the identification of key
sequences and circuits controlling the relevant immune
reactions. This will require innovative, interdisciplinary and
collaborative strategies of a scale and complexity we are only now
beginning to comprehend.
Specific problems addressed include the following:
* What kinds of information are we lacking to understand how the
genome sequence specifies the differentiation and response of
immune system cells, and system behaviour such as immunological
memory and tolerance?
* Which genome sequences and cellular circuits cause or prevent
pathological immune responses to foreign pathogens, allergens or
self-tissues?
* Which host and pathogen genome sequences and cellular circuits
explain the failure of sterilizing immune responses to
sophisticated human pathogens such as the agents of tuberculosis,
malaria, metazoan parasites and chronic viruses?
Containing contributions from a range of leading experts in the
field, this book provides an important new perspective for clinical
immunologists and basic researchers alike.
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