Vascular Development
Fr. 155.00
inkl. MwStBeschreibung
Details
Format
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
20.08.2007
Herausgeber
Derek J. Chadwick + weitereVerlag
John Wiley & Sons IncSeitenzahl
260 (Printausgabe)
Dateigröße
4068 KB
Auflage
1. Auflage
Sprache
Englisch
EAN
9780470319420
The formation of blood vessels is an essential aspect of
embryogenesis in vertebrates. It is a central feature of
numerous post-embryonic processes, including tissue and organ
growth and regeneration. It is also part of the pathology of
tumour formation and certain inflammatory conditions.
In recent years, comprehension of the molecular genetics of
blood vessel formation has progressed enormously and studies in
vertebrate model systems, especially the mouse and the zebrafish,
have identified a common set of molecules and processes that are
conserved throughout vertebrate embryogenesis while, in addition,
highlighting aspects that may differ between different animal
groups.
The discovery in the past decade of the crucial role of new
blood vessel formation for the development of cancers has generated
great interest in angiogenesis (the formation of new blood vessels
from pre-existing ones), with its major implications for potential
cancer-control strategies. In addition, there are numerous
situations where therapeutic treatments either require or would be
assisted by vasculogenesis (the de novo formation of blood
vessels). In particular, post-stroke therapies could include
treatments that stimulate neovascularization of the affected
tissues.
The development of such treatments, however, requires thoroughly
understanding the developmental properties of endothelial cells and
the basic biology of blood vessel formation.
While there are many books on angiogenesis, this unique book
focuses on exactly this basic biology and explores blood vessel
formation in connection with tissue development in a range of
animal models. It includes detailed discussions of relevant cell
biology, genetics and embryogenesis of blood vessel formation and
presents insights into the cross-talk between developing blood
vessels and other tissues.
With contributions from vascular biologists, cell biologists and
developmental biologists, a comprehensive and highly
interdisciplinary volume is the outcome.
embryogenesis in vertebrates. It is a central feature of
numerous post-embryonic processes, including tissue and organ
growth and regeneration. It is also part of the pathology of
tumour formation and certain inflammatory conditions.
In recent years, comprehension of the molecular genetics of
blood vessel formation has progressed enormously and studies in
vertebrate model systems, especially the mouse and the zebrafish,
have identified a common set of molecules and processes that are
conserved throughout vertebrate embryogenesis while, in addition,
highlighting aspects that may differ between different animal
groups.
The discovery in the past decade of the crucial role of new
blood vessel formation for the development of cancers has generated
great interest in angiogenesis (the formation of new blood vessels
from pre-existing ones), with its major implications for potential
cancer-control strategies. In addition, there are numerous
situations where therapeutic treatments either require or would be
assisted by vasculogenesis (the de novo formation of blood
vessels). In particular, post-stroke therapies could include
treatments that stimulate neovascularization of the affected
tissues.
The development of such treatments, however, requires thoroughly
understanding the developmental properties of endothelial cells and
the basic biology of blood vessel formation.
While there are many books on angiogenesis, this unique book
focuses on exactly this basic biology and explores blood vessel
formation in connection with tissue development in a range of
animal models. It includes detailed discussions of relevant cell
biology, genetics and embryogenesis of blood vessel formation and
presents insights into the cross-talk between developing blood
vessels and other tissues.
With contributions from vascular biologists, cell biologists and
developmental biologists, a comprehensive and highly
interdisciplinary volume is the outcome.
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