Pseudogenes
Band 1167

Pseudogenes

Functions and Protocols

Fr. 149.00

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Pseudogenes

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ab Fr. 149.00
eBook

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ab Fr. 137.90

Beschreibung

Details

Einband

Taschenbuch

Erscheinungsdatum

24.09.2016

Herausgeber

Laura Poliseno

Verlag

Springer Us

Seitenzahl

319

Beschreibung

Details

Einband

Taschenbuch

Erscheinungsdatum

24.09.2016

Herausgeber

Laura Poliseno

Verlag

Springer Us

Seitenzahl

319

Maße (L/B/H)

25.4/17.8/1.9 cm

Gewicht

626 g

Auflage

Softcover reprint of the original 1st ed. 2014

Sprache

Englisch

ISBN

978-1-4939-4646-4

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  • Pseudogenes

  • Part I: Introductory Chapters

     

    1. Pseudogene Redux with New Biological Significance

                Leonardo Salmena

     

    2. Contribution of Pseudogenes to Sequence Diversity

                Mauno Vihinen

     

    Part II: Methods to Identify Pseudogenes

     

    3. Computational Methods for Pseudogene Annotation Based on Sequence Homology

                Paul M. Harrison

     

    4. Computational Methods of Identification of Pseudogenes Based on Functionality: Entropy and GC Content

                Evgeniy S. Balakirev, Vladimir R. Chechetkin, Vasily V. Lobzin, and Francisco J. Ayala

     

    5. Computational Methods of Identification of Pseudogenes Based on Functionality: Hybridization of 18S rRNA and mRNA During Translation

                Chuanhua Xing

     

    6. Whole Genome Identification of Neutrally Evolving Pseudogenes Using the Evolutionary Measure dN/dS

                Lisa O. Andrieux and David Torrents Arenales

     

    7. Methods to Study the Occurrence and the Evolution of Pseudogenes Through a Phylogenetic Approach

                Jacques Dainat and Pierre Pontarotti

     

    Part III: Methods to Detect Transcribed Pseudogenes of a Parental Gene of Interest

     

    8. Methods for Detecting Transcribed Pseudogenes: PCR on Regions of High Sequence Similarity Followed by Cloning and Sequencing

                Wenyong Ding and Jianwu Dai

     

    Part IV: High-Throughput Methods to Detect Transcribed Pseudogenes

     

    9. RNA Amplification for Pseudogene Detection Using RNA-Seq

                Stephen C.M. Tsoi and Michael K. Dyck

     

    10. GENCODE Pseudogenes

                Adam Frankish and Jennifer Harrow

     

    11. Methods to Detect Transcribed Pseudogenes: RNA-Seq Discovery Allows Learning Through Features

                Camilo Valdes and Enrico Capobianco

     

    Part V: High-Throughput Methods to Detect Translated Pseudogenes

     

    12. Proteomics Techniques for the Detection of Translated Pseudogenes

                Nadia Ucciferri and Silvia Rocchiccioli

     

    Part VI: Methods to Study Transcribed Pseudogenes

     

    13. Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation

                Florian A. Karreth, Ugo Ala, Paolo Provero, and Pier Paolo Pandolfi

     

    14. Pseudogenes: A Novel Source of Trans Acting Antisense RNAs

                Per Johnsson, Kevin V. Morris, and Dan Grandér

     

    15. Pseudogene-Derived Endogenous siRNAs and Their Function

                Wen-Ling Chan and Jan-Gowth Chang

     

    Part VII: Methods to Study Translated Pseudogenes

     

    16. Methods to Study Translated Pseudogenes: In Vitro Translation, Fusion with a Tag/Reporter Gene, and Complementation Assay

                Anne Parle-McDermott

     

    Part VIII: Methods to Study Translated Pseudogenes

     

    17. Targeted and Robust Amplification of Mitochondrial DNA in the Presence of Nuclear Encoded Mitochondrial Pseudogenes Using Φ29 DNA Polymerases

                Jonci N. Wolff

     

    18. Discrimination of Pseudogene and Parental Gene DNA Methylation Using Allelic Bisulphite Sequencing

                Luke B. Hesson and Robyn L. Ward

     

    19. Mutational Analysis of CYP21A2 Gene and CYP21A1P Pseudogene: Long Range PCR on Genomic DNA

                Hsien-Hsiung Lee

     

    20. PMS2 Gene Mutational Analysis: RNA-Based Direct cDNA Sequencing to Circumvent Pseudogene Interference

                Katharina Wimmer and Annekatrin Wernstedt

     

    21. Dealing with Pseudogenes in Molecular Diagnostics in the Next Generation Sequencing Era

    Kathleen Claes and Kim De Leeneer