Meine Filiale

Superantigens

Current Topics in Microbiology and Immunology Band 174

Buch (Taschenbuch, Englisch)
Buch (Taschenbuch, Englisch)
Fr. 135.00
Fr. 135.00
inkl. gesetzl. MwSt.
inkl. gesetzl. MwSt.
Versandfertig innert 4 - 7 Werktagen Versandkostenfrei
Versandfertig innert 4 - 7 Werktagen
Versandkostenfrei

Weitere Formate

Beschreibung

This volume of Current Topics in Microbiology and Immunology is concerned with a class of molecules that are the most potent polyclonal stimulators of T lymphocytes of several species. These molecules have been named "superantigens" because they use a mechanism of T cell stimulation closely mimicking MHC-restricted recognition of specific antigen: they act on variable parts of T cell antigen receptors and are presented by MHC class II molecules. Prototypes of these molecules are the pyrogenic exotoxins produced by S. aureus and S. pyogenes, of which the staphylococcal enterotoxins and the toxic shock syndrome toxin are the best known. Superantigens also occur endogen ously in mice, most notably the enigmatic Mis determinants, that have withstood characterization for nearly 20 years. Only very recently was it found that Mis is probably encoded by endogenous retroviruses. The list of candidates that are implicated as being superantigens is growing. In many cases, however, the proof that a given molecule indeed falls into this category is still missing.

Bernhard Fleischer ist Abteilungsleiter und Lehrer an der Fachschule Maschinenbautechnik in Mönchengladbach mit Schwerpunkt Entwicklung und Konstruktion von Maschinen und Betriebsmitteln.

Produktdetails

Einband Taschenbuch
Herausgeber Bernhard Fleischer, Hans O. Sjögren
Seitenzahl 137
Erscheinungsdatum 26.05.2012
Sprache Englisch
ISBN 978-3-642-51000-7
Verlag Springer Berlin
Maße (L/B/H) 23.5/15.5/0.8 cm
Gewicht 248 g
Abbildungen 5 schwarzweisse Abbildungen, 15 Tabellen
Auflage Softcover reprint of the original 1st ed. 1991

Weitere Bände von Current Topics in Microbiology and Immunology

Kundenbewertungen

Es wurden noch keine Bewertungen geschrieben.
  • Artikelbild-0
  • Molecular Genetics of Pyrogenic Exotoxin “Superantigens” of Group A Streptococci and Staphylococcus aureus.- T Cell Recognition of Superantigens.- T Cell Activation by Superantigens—Dependence on MHC Class II Molecules.- The Human T Cell Response to Mitogenic Microbial Exotoxins.- Toxic Shock Syndrome Toxin-1, Toxic Shock, and the Immune System.- Staphylococcal Enterotoxin-Dependent Cell-Mediated Cytotoxicity.- CD4/CD8 Coreceptor-Independent Costimulator-Dependent Triggering of SEB-Reactive Murine T Cells.- The Immunobiology of Mycoplasma arthritidis and its Superantigen MAM.- The Anti-CD3-Induced Syndrome: A Consequence of Massive In Vivo Cell Activation.