Band 266
The hERG Cardiac Potassium Channel Structure, Function and Long QT Syndrome. No. 266
Aus der Reihe
Novartis Foundation Symposium
Fr. 227.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
01.04.2005
Herausgeber
Derek J. Chadwick + weitereVerlag
John Wiley & SonsSeitenzahl
308
Maße (L/B/H)
24/16.2/2.4 cm
Gewicht
626 g
Auflage
1. Auflage
Sprache
Englisch
ISBN
978-0-470-02140-8
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding.
It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks.
Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.
It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks.
Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.
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