• Produktbild: The Human Oncogenic Viruses
  • Produktbild: The Human Oncogenic Viruses

The Human Oncogenic Viruses Molecular Analysis and Diagnosis

Aus der Reihe The Oncogenes

Fr. 139.00

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.08.1986

Verlag

Humana Press

Seitenzahl

281

Maße (L/B/H)

23.4/15.6/1.8 cm

Gewicht

594 g

Auflage

1986 edition

Sprache

Englisch

ISBN

978-0-89603-088-6

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.08.1986

Verlag

Humana Press

Seitenzahl

281

Maße (L/B/H)

23.4/15.6/1.8 cm

Gewicht

594 g

Auflage

1986 edition

Sprache

Englisch

ISBN

978-0-89603-088-6

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: The Human Oncogenic Viruses
  • Produktbild: The Human Oncogenic Viruses
  • Cytogenetics of the Leukemias and Lymphomas.- 1. Introduction.- 2. Methodologie Background and Considerations.- 3. Chromosome Changes in Chronic Myelocytic Leukemia (CML).- 3.1. The Philadelphia (Ph) Chromosome.- 3.2. Cytogenetics of the Blastic Phase.- 4. Oncogenes, the Ph, and CML.- 5. Karyotypic Aspects of the Acute Leukemias.- 5.1. Acute Nonlymphocytic Leukemia (ANLL).- 5.2. Acute Lymphoblastic Leukemia (ALL).- 6. Preleukemia and Myelodysplastic Disorders.- 7. Cytogenetic Changes in Chronic Lymphocytic Leukemia (CLL).- 7.1. B- and T-Cell Mitogenic Stimulants.- 7.2. B- and T-Cell CLL.- 7.3. Prolymphocytic Leukemia.- 8. Cytogenetic Aspects of Lymphoma.- 8.1. Burkitt’s Lymphoma.- 8.2. Malignant Lymphomas (Other Than Burkitt’s).- 9. Diagnostic and Prognostic Aspects of Chromosome Changes in Leukemia and Lymphoma.- 9.1. Specific (Primary) Changes.- 9.2. Primary vs Secondary Chromosome Changes.- References.- Cytogenetics of Solid Tumors: Renal Cell Carcinoma, Malignant Melanoma, Retinoblastoma, and Wilms’ Tumor.- 1. Introduction.- 2. Materials and Procedures.- 2.1. Tissue Culture Techniques.- 2.2. Harvesting and Chromosome Preparation.- 2.3. Chromosome Banding Techniques.- 3. Renal Cell Carcinoma (RCC).- 3.1. General Description.- 3.2. Chromosome Anomalies in RCC.- 4. Malignant Melanoma (MM).- 4.1. General Description.- 4.2. Chromosome Anomalies in MM.- 5. Retinoblastoma (RB).- 5.1. General Description.- 5.2. Chromosome Anomalies in RB.- 6. Wilms’ Tumor (WT).- 6.1. General Description.- 6.2. Chromosome Anomalies in WT.- 7. Discussion.- 7.1. General Discussion.- 7.2. Double Minutes and Homogeneously Staining Regions.- 8. Concluding Remarks.- References.- Elucidation of a Normal Function for a Human Proto-Oncogene.- 1. Introduction.- 2. A Primate Sarcoma Virus with Novel Properties.- 3. Molecular Cloning of the Biologically Active SSV Genome.- 4. Molecular Organization of the SSV Genome.- 5. Detection and Localization of a Non-SSAV-Related Region of SSV.- 6. v-sis Is Cell Derived and Required for SSV Transforming Activity.- 7. Predicted Coding Sequence of the SSV Transforming Gene.- 8. Detection of the SSV Transforming Gene Product.- 9. p28sis Is Related to Human Platelet-Derived Growth Factor.- 10. Close Structural and Conformational Similarity Between the SSV Transforming Gene Product and Biologically Active PDGF.- 11. Anti-PDGF Serum Recognizes SSV Transforming Gene Products.- 12. The Human c-sis Locus.- 13. Mechanism of SSV Transformation.- References.- Detection of HSV-2 Genes and Gene Products in Cervical Neoplasia.- 1. Introduction.- 2. Etiologic Factors.- 2.1. Sexual Factors.- 2.2. Epidemiologic Factors.- 2.3. Male Role.- 2.4. Hereditary Factors.- 2.5. Chemical Factors.- 2.6. Radiation.- 2.7. Infectious Agents.- 3. Herpes Genitalis Infections.- 3.1. Productive Infections.- 3.2. Latent Infections.- 4. Pathologic Features of Cervical Neoplasia.- 5. Seroepidemiologic Studies Linking HSV-2 to Cervical Neoplasia.- 6. Herpes-Specific Antigens in Cervical Neoplasia.- 7. HSV Genetic Sequences in Cervical Neoplasia.- 8. Postulated Mechanisms of Oncogenesis for Cervical Neoplasia.- References.- Papillomaviruses in Anogenital Neoplasms.- 1. Introduction.- 2. Papillomavirus Properties.- 2.1. Chemical Composition.- 2.2. Papillomavirus Plurality.- 2.3. Evolutionary Relatedness.- 2.4. Papillomavirus Genome Function.- 2.5. Virus Host-Cell Interactions.- 3. Evidence for the Association of HPV with Anogenital Neoplasia.- 3.1. Immunological Studies.- 3.2. DNA Hybridization.- 4. Detection of HPV Structural Antigens.- 4.1. Method of Analysis.- 4.2. Interpretation of Results.- 5. Detection of HPV DNA Sequences.- 5.1. Methods of Analysis.- 5.2. Interpretation of Results.- 6. Papillomaviruses and Cancer.- References.- Human Epstein-Barr Virus and Cancer.- 1. Introduction.- 2. EBV Virion, Antigens, and Genome.- 2.1. EBV Virion.- 2.2. EBV-Related Antigens.- 2.3. EBV Genome.- 3. Oncogenicity of EBV.- 3.1. Oncogenicity Properties of EBV.- 3.2. In Vitro Transformation of Human Lymphocytes of EBV.- 3.3. Experimental Tumorigenesis In Vivo by EBV.- 4. Ubiquity of EBV in Humans.- 4.1. Natural History of EBV Infections in Humans.- 4.2. Abnormality in Natural History of EBV Infection.- 5. Epstein-Barr Virus and Human Cancer.- 5.1. Burkitt’s Lymphoma and EBV.- 5.2. EBV and Nasopharyngeal Carcinoma.- 5.3. EBV and Opportunistic Lymphoma.- 6. Protection Against EBV-Induced Oncogenesis.- 6.1. Possible Defense Mechanism.- 6.2. EBV Vaccine.- 7. Summary.- References.- Hepatitis B Virus and Hepatocellular Carcinoma.- 1. Introduction.- 2. Structure and Biology of Hepatitis B Virus.- 2.1. Structure of the Hepatitis B Virus.- 2.2. Structure of the Hepatitis B Virus Genome.- 2.3. Genetic Organization of the Hepatitis B Virus Genome.- 2.4. Replication of the Hepatitis B Virus Genome.- 3. Molecular Analyses of Hepatitis B Virus Infection and Hepatocellular Carcinoma.- 3.1. Immunochemical Detection of Viral Antigens.- 3.2. Molecular Hybridization Analyses.- 4. Presence of Hepatitis B Virus DNA in Nonhepatocytes.- 5. Presence, State, and Molecular Structure of Hepatitis B Viral DNA in Hepatocellular Carcinoma.- 5.1. Presence of Viral DNA in Hepatocellular Carcinoma.- 5.2. State of Viral DNA in Hepatocellular Carcinoma.- 5.3. Molecular Structure of Intregrated Viral DNA Sequences and Relation to Host Cellular Genome.- 6. Expression of Viral Genes in Hepatocellular Carcinoma.- 7. Molecular Mechanisms of Malignant Transformation of Hepatocytes.- 8. Epidemiology of Hepatocellular Carcinoma.- 8.1. Geographic Distribution.- 8.2. Role of HBV and Cirrhosis.- 8.3. Sex, Genetic, and Host Factors.- 8.4. Aflatoxin B1 and HBV in Hepatocellular Carcinoma.- 9. Clinical Aspects of Hepatocellular Carcinoma.- 9.1. Presenting Signs and Symptoms.- 9.2. Paraneoplastic Manifestations.- 9.3. Laboratory Tests.- 9.4. Diagnosis.- 9.5. Treatment.- 9.6. Natural History and Prognosis.- 9.7. Strategies of Prophylaxis Against HBV and Prevention of Hepatocellular Carcinoma.- 10. Summary and Conclusions.- References.- Kaposi’s Sarcoma: Acquired Immunodeficiency Syndrome (AIDS) and Associated Viruses.- 1. Introduction.- 2. Kaposi’s Sarcoma.- 2.1. Description.- 2.2. Epidemiology.- 2.3. Relation to Immunosuppression.- 3. Kaposi’s Sarcoma and AIDS.- 3.1. Introduction.- 3.2. Epidemiology.- 4. KS and HLA.- 4.1. DR5 Association.- 4.2. Other Associations.- 4.3. HLA-DR Associated Diseases.- 5. KS and CMV.- 5.1. Viral Particles and Antigen.- 5.2. Seroepidemiology.- 5.3. CMV Genomic Material.- 5.4. AIDS-Associated KS and CMV.- 6. AIDS-Etiologic Agent.- 6.1. Background.- 6.2. CMV.- 6.3. Retroviruse.- 7. African KS and AIDS.- 8. Summary.- References.