Dafas, P: Computational algorithms for protein-protein inter Rule discovery from gene expression data and effective protein interaction inference in molecular structures
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- Englisch ausgewählt
Fr. 78.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
01.08.2009
Verlag
VDMSeitenzahl
136
Maße (L/B/H)
22/15/0.8 cm
Gewicht
219 g
Sprache
Englisch
ISBN
978-3-639-18597-3
The experimental measurement of gene expression levels has produced preliminary results on the regulation, pathways and networks of genes in cells. Furthermore, the number of available three- dimensional folded structures of proteins increases on a daily basis. The ultimate aim of both genomics and proteomics from the perspective of bioinformatics, is to map out all the circuits of energy and information processing in life by terms of molecular interactions in a systematic way with minimal human intervention. In this book the author presents a new rule mining framework for "in silico" inference of protein-protein interactions and an effective class of techniques that identify domain- domain interactions from multiple domain protein structures. The above two approaches allow molecular biologists to use both gene expression data and three dimensional folded protein structures to efficiently predict or validate potential protein- protein interactions.
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