Produktbild: Steroid Chemistry at a Glance

Steroid Chemistry at a Glance

Aus der Reihe Chemistry At a Glance

Fr. 69.90

inkl. gesetzl. MwSt., Versandkostenfrei


Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.11.2010

Verlag

John Wiley & Sons

Seitenzahl

152

Maße (L/B/H)

29.5/20.8/0.8 cm

Gewicht

428 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-66084-3

Beschreibung

Rezension

"Overall, this timely book is a valuable addition to the stable. It is applicable to both chemistry and pharmacy undergraduate curricula, unlocking part of the wealth of chemistry that is the legacy of the great 20th century steroid chemistry effort." (Chemistry World, 1 October 2011)

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.11.2010

Verlag

John Wiley & Sons

Seitenzahl

152

Maße (L/B/H)

29.5/20.8/0.8 cm

Gewicht

428 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-66084-3

Kundinnen und Kunden meinen

0 Bewertungen

Informationen zu Bewertungen

Zur Abgabe einer Bewertung ist eine Anmeldung im Konto notwendig. Die Authentizität der Bewertungen wird von uns nicht überprüft. Wir behalten uns vor, Bewertungstexte, die unseren Richtlinien widersprechen, entsprechend zu kürzen oder zu löschen.

Die Bewertungen sind nach Format, Anzahl Sterne und Datum sortiert.

Verfassen Sie die erste Bewertung zu diesem Artikel

Helfen Sie anderen Kund*innen durch Ihre Meinung

Kundinnen und Kunden meinen

0 Bewertungen filtern

Die Leseprobe wird geladen.
  • Produktbild: Steroid Chemistry at a Glance
  • Preface.
     
    Introduction.
     
    1 Steroids: a Brief History.
     
    1.1 Structure Determination.
     
    1.1.1 Cholesterol and Cholic Acid.
     
    1.1.2 The Sex Steroids.
     
    1.1.3 Corticosteroids.
     
    2 Sources of Steroids.
     
    2.1 Biosynthesis.
     
    2.2 Commercial Steroid Starting Materials.
     
    2.2.1 Diosgenin.
     
    2.2.2 Soybean Sterols.
     
    3 Estranes: Steroids in Which Ring A is Aromatic.
     
    3.1 Biological Activity.
     
    3.2 Sources of Estranes.
     
    3.2.1 From Androstanes.
     
    3.2.2 Estrogens by Total Synthesis.
     
    3.3 Chemical Reactions of Estranes.
     
    3.3.1 Aromatic A-ring Reactions.
     
    3.3.2 Modifications on Ring B.
     
    3.3.3 Modifications on Ring C.
     
    3.3.4 Modifications on Ring D.
     
    3.4. Some Drugs Based on Estranes.
     
    4 Gonanes or 19-nor-Steroids.
     
    4.1 Preparation of Gonane Starting Materials.
     
    4.1.1 Birch Reduction.
     
    4.1.2 Synthesis by Sequential Annulation Reactions.
     
    4.2 Anabolic-Androgenic Gonanes.
     
    4.2.1 Biological Activity.
     
    4.2.2 Synthesis of 19-Norandrogens.
     
    4.3 Progestational Gonanes.
     
    4.3.1 Biological Activity.
     
    4.3.2 Preparation of 19-Norprogestins.
     
    4.4 Some Drugs Based on Gonanes.
     
    4.4.1 Androgenic-Anabolic Agents.
     
    4.4.2 Progestins.
     
    4.4.3 Progestin Antagonists.
     
    5 Androstanes, C19 Steroids and Their Derivatives.
     
    5.1 Biological Activity.
     
    5.2 Sources of Androstanes.
     
    5.2.1 From Pregnenolone.
     
    5.2.2 Fermentations.
     
    5.2.3 Total Synthesis.
     
    5.3 Modified Anabolic-Androgenic Androstanes.
     
    5.3.1 17-Desalkyl Compounds.
     
    5.3.2 17-Alkyl Compounds.
     
    5.3.3 Modifications on Ring B.
     
    5.3.4 Modifications on Ring C.
     
    5.3.5 Modifications on Ring D.
     
    5.4 17-Spirobutyrolactone Aldosterone Antagonists.
     
    5.5 Some Drugs Based on Androstanes.
     
    5.5.1 Androgens.
     
    5.5.2 Spirobutyrolactones.
     
    6 Pregnanes, Part 1: Progestins.
     
    6.1 Biological Activity.
     
    6.2 Sources of Progesterone.
     
    6.2.1 From Phytochemicals.
     
    6.2.2 By Total Synthesis.
     
    6.2.3 From Dehydroepiandrosterone (DHEA) Acetate.
     
    6.3 Modified Pregnanes.
     
    6.3.1 17-Hydroxy and Acyloxy Derivatives.
     
    6.3.2 Modifications on Ring A.
     
    6.3.3 Modifications on Ring B.
     
    6.3.4 General Methods for Modifications on Ring D.
     
    6.3.5 More Progesterone Analogues.
     
    6.4 Some Drugs Based on Progestins.
     
    6.4.1 Medroxyprogesterone Acetate (10-2).
     
    6.4.2 Megestrol Acetate (10-3).
     
    6.4.3 Melengestrol Acetate (26-7).
     
    7 Pregnanes, Part 2: Corticosteroids.
     
    7.1 Biological Activity.
     
    7.2 Sources of Corticoids.
     
    7.2.1. Introduction of Oxygen at C11.
     
    7.2.2 Construction of the Dihydroxyacetone Side Chain.
     
    7.3 Modified Corticoids.
     
    7.3.1 Unsaturation.
     
    7.3.2 Additional Alkyl Groups.
     
    7.3.3 Halogenated Corticoids.
     
    7.3.4 Hydroxylation: 16,17-Diols.
     
    7.3.5 Corticoids with Multiple Modifications.
     
    7.3.6 Miscellaneous Corticoids.
     
    7.4 Some Drugs Based on Corticoids.
     
    8 Miscellaneous Steroids.
     
    8.1 Heterocyclic Steroids.
     
    8.1.1 Introduction.
     
    8.1.2 Steroids with a Heteroatom in Ring A.
     

    8.1.3 Steroids with a Heteroatom in Ring B.
     
    8.1.4 Steroids with a Heteroatom in Ring C.
     
    8.1.5 Steroids with a Heteroatom in Ring D.
     
    8.2 Ca