Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
28.02.2011
Verlag
LAP LAMBERT Academic PublishingSeitenzahl
68
Maße (L/B/H)
22/15/0.5 cm
Gewicht
119 g
Auflage
1. Auflage
Sprache
Englisch
ISBN
978-3-8443-1346-8
Streptococcus mutans has been identified as the major etiological agent of dental caries. The evidence of a specific bacterial cause of dental caries and of the function of the salivary glands as an effector site of the mucosal immune system has provided a scientific basis for the development of a vaccine against this highly prevalent and costly oral disease. Research efforts towards developing an effective and safe caries vaccine have been facilitated by progress in molecular biology, with the cloning and functional characterization of virulence factors from mutans streptococci, the principal causative agent of dental caries. Immunization when infants are about one year old may establish effective immunity against an ensuing colonization attempts by mutans streptococci. The present review critically evaluates recent progress in this field of dental research and attempts to stress the protective potential as well as limitations of caries immunization.
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