• Produktbild: Endemic Cretinism
  • Produktbild: Endemic Cretinism

Endemic Cretinism

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

26.09.2011

Herausgeber

John Dennison + weitere

Verlag

Springer Us

Seitenzahl

215

Maße (L/B/H)

24.1/16/1.6 cm

Gewicht

518 g

Auflage

2011

Sprache

Englisch

ISBN

978-1-4614-0280-0

Beschreibung

Rezension

From the reviews:

“There are still areas in the world in which the population suffers from iodine deficiency, and so this book will be of interest. This volume is the first English translation of the book published in German in 1936. … Of interest to Public Health workers and endocrinologists.” (Pediatric Endocrinology Reviews (PER), Vol. 10 (2), January, 2013)

“This book addresses a re-emerging world problem identified, namely the role of iodine deficiencies on cognitive and other mental dysfunctions. … This book serves to provide clinical approaches for treatment while also raising public awareness of this sad and growing problem.” (The Electric Review, October, 2012)

Zitat

From the reviews:"This book addresses a re-emerging world problem identified, namely the role of iodine deficiencies on cognitive and other mental dysfunctions. ... This book serves to provide clinical approaches for treatment while also raising public awareness of this sad and growing problem." (The Electric Review, October, 2012)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

26.09.2011

Herausgeber

Verlag

Springer Us

Seitenzahl

215

Maße (L/B/H)

24.1/16/1.6 cm

Gewicht

518 g

Auflage

2011

Sprache

Englisch

ISBN

978-1-4614-0280-0

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Endemic Cretinism
  • Produktbild: Endemic Cretinism
  • Introduction 

    Chapters

    I. Etymology of the word ‘cretin’  (Wegelin) 

    II. Definition  (de Quervain)

    III. Historical (Wegelin) 

    IV. Epidemiology (Wegelin)

     1.  Statistics 

     2.  Geographical distribution

      Europe 

      Asia 

      Australia 

      Africa 

      America 

     3.  Racial affinity

     4.  Relation to endemic goitre

    V. Course and clinical pattern of cretinism (de Quervain) 

      Cretinism with and without goitre 

      Grade of cretinism

      Development of cretins

      Deterioration

      Spontaneous recovery

      Influence of endemic goitre on children

     1.  The sexual distribution of cretinism

     2.  The behaviour of physical development 

      Growth in non-goitrous cretins

      Growth in goitrous cretins 

      Development quotient

      a)  The individual  parts of the skeleton 

       Behaviour of the skull

       Cranial capacity 

       Dentition

       Remainder of skeleton 

       Appearance of centres of ossification

       Joints 

       Cretin hips

       Humerus varus 

       Pelvis 

      b)  The skin and its appendages

       Myxœdema 

       Skin shade 

       Dryness of the skin 

       Hair growth 

      c)  The musculature 

      d)  The behaviour of the endocrine glands 

       The thyroid gland 

       Atrophy of the thyroid 

       Cretinous goitre 

       The parathyroid glands

       The sexual glands and the sexual organs 

       Hypophysis 

      e)  The intestinal tract and its glands 

      f)  The blood vascular system 

       Heart 

       Capillary structure 

      g)  The nervous system

       Mobility 

       Neuromuscular system

       Tendon reflexes 

       MacCarrison’s ‘Nervous cretinism’  

       Sense organs    Hearing disorders     

       Speech disorders 

       Autonomic nervous system 

     3.  The intellectual behaviour of cretins 

       Mental debility     

       Intellectual development 

       Acquisitive instinct

       Imitative behaviour 

       Self-awareness 

       Emotions     

       Sociability 

       Gratitude 

       Sexual behaviour     

       Psychological functions in relation to body type 

    VI.  Pathological anatomy and histology (Wegelin) 

     1. Thyroid gland 

       Epithelial changes 

       Sclerosis 

       Lymphocyte infiltration 

       Vascularization 

       Regenerative epithelial growth 

       Nodular goitre 

       Malignant epithelial goitr 

       Vascularisation of nodular goitre     

       Functional behaviour of the thyroid gland 

       Diffuse goitre 

       ‘Niduses’ of squamous epithelium 

       Dispersed aggregations of parathyroid cells and remnants of

       the ultimobranchial body 

     2. Parathyroid glands 

     3. Thymus 

     4. Hypophysis 

     5. Pineal gland 

     6. Suprarenal glands 

     7. Gonads 

       A.  Male gonads

       B.  Female gonads 

        Ovaries

        Uterus                Breasts

      8. Nervous system  

        Meninges 

        Brain

        Spinal cord 

        Peripheral nerves 

      9. Musculature 

      10. The skeleton

        General restriction in growth 

        Physical proportions 

        Development

        Bone form relationships 

        Skull 

        Trunk 

        Upper limbs      

        Lower limbs 

     11. Joints 

     12. Teeth 

     13. Skin and subcutaneous tissue 

     14. Ear 

     15. Circulatory system    Heart

        Arteries 

        Capillaries 

     16. Blood, and blood-forming organs 

        Blood

        Bone marrow 

        Lymph glands 

        Spleen 

     17. Respiratory organs 

     18. Digestive organs 

        Tongue      

        Stomach and intestine

        Pancreas 

        Liver 

        Gall bladder 

        Peritoneum 

     19. Urinary system 

     20. Further anatomical findings      

        Malformations

        Blastoma 

        Tuberculosis

        Syphilis

     21. Lifespan and diseases of cretins 

       Average age 

       Causes of death 

     22. Cretinism in animals 

     23. Summary 

    VII.  Pathological physiology  (de Quervain) 

       Endemic thyropathy

       Metabolism

       Albumen and salt metabolism     

       Carbohydrate metabolism and basal respiratory metabolism 

       Blood examination 

       Blood clotting 

       Sedimentation rate of red blood cells 

       Dispersion grade of blood albumen bodies     

       Analysis of the individual fractions of albumen bodies in the blood

       by weight determination

       Phagocytic activity of leucocytes

       Ion relationships in the blood 

       Iodine distribution among cretins

       Analysis of the iodine level in the blood

       Testing of thyroid gland function, after Asher-Streuli 

       Functional behaviour of the liver 

       Basedow appearance among cretins 

    VIII.  Pathogenesis  (de Quervain and Wegelin) 

       Comparison of cretinism with congenital athyrosis, spontaneous

       myxœdema and postoperative myxœdema     

       Scheme of possible influences of the goitre-noxa  

       Possibility of a dysthyrosis 

       Occurrence of thyroid gland atrophy    Congenital goitre among cretins

       Comparison of the anatomical findings with those

       of congenital athyrosis 

       Dissociation of symptoms 

       Different threshold values of thyroid gland function 

       Heredity 

       Goitre in the mother     

       Geographical dependence of goitre and cretinism 

       Inbreeding

       Significance of local factors 

       Relationship with Status degenerativus

       Question on the occurrence of genotypically-inheritable,

       non-site-dependent diseases due to the goitre-noxa 

       Varying powers of resistance to the goitre-noxa 

       Goitre investigations in twins 

       Question about direct exogenous influence on the embryo 

       Possibility of direct exogenous influence of other endocrine glands

       by the goitre-noxa 

       Nervous cretinism

       Question on the inadequate functioning of the other endocrine glands 

       Occurrence of hearing disorders 

    IX.  Prophylaxis and Treatment of Cretinism  (de Quervain) 

       ‘Racial hygiene’     

       Improvement of the hygiene of living conditions 

       Radioactivity of the soil 

       Combating the goitre-noxa by iodine in small doses 

       Prophylaxis through iodised cooking salt     

       Iodine supplement during school age 

       Iodine supplement for the pregnant mother 

       The question of sterilization

       Implantation of thyroid gland tissue 

       Substitution therapy with thyroid gland preparations 

       Iodine treatment 

       Goitre surgery among cretins 

       Goitre and cancer 

    References 

    Appendix