Produktbild: Whole Body Hyperthermia: Biological and Clinical Aspects

Whole Body Hyperthermia: Biological and Clinical Aspects

Aus der Reihe Clinical Thermology

Fr. 72.90

inkl. gesetzl. MwSt., Versandkostenfrei


Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

25.01.2012

Herausgeber

Michel Gautherie

Verlag

Springer Berlin

Seitenzahl

84

Maße (L/B/H)

27/19.3/0.6 cm

Gewicht

229 g

Auflage

Softcover reprint of the original 1st ed. 1992

Sprache

Englisch

ISBN

978-3-642-84598-7

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

25.01.2012

Herausgeber

Michel Gautherie

Verlag

Springer Berlin

Seitenzahl

84

Maße (L/B/H)

27/19.3/0.6 cm

Gewicht

229 g

Auflage

Softcover reprint of the original 1st ed. 1992

Sprache

Englisch

ISBN

978-3-642-84598-7

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: Whole Body Hyperthermia: Biological and Clinical Aspects
  • 1 Introduction.- 1.1 Background.- 1.2 Systemic versus Local and Regional Hyperthermia.- 1.3 Conceptual Approaches to the Therapeutic Use of WBH.- 1.3.1 Drugs.- 1.3.2 Immunotherapy.- 1.3.3 Radiotherapy.- 1.4 Summary.- 2 Hyperthermia and the Immune System.- 2.1 Introduction.- 2.2 In Vitro Studies of Hyperthermia and Immune Effector Cells.- 2.2.1 Macrophages and Hyperthermia.- 2.2.2 Hyperthermia and NK Cells.- 2.2.3 In Vitro Hyperthermia and Biological Response Modifiers.- 2.3 In Vivo Studies: The Abscopal Response and Metastasis.- 2.3.1 NK cells In Vivo.- 2.3.2 Metastasis and Hyperthermia.- 2.4 Clinical Hyperthermia and the Abscopal Response.- 2.5 Clinical WBH and the Immune Response.- 2.6 Conclusions.- 3 WBH and Ionizing Irradiation.- 3.1 Background.- 3.2 Potential Advantages of WBH Compared to Local Hyperthermia.- 3.3 The Importance of Treatment Temperatures Used in Preclinical Studies.- 3.4 Possibly Controllable Clinical Treatment Variables.- 3.5 Clinical Investigations Combining WBH and Ionizing Irradiation.- 3.6 Summary.- 4 WBH and Chemotherapy.- 4.1 Introduction.- 4.2 Potential Mechanisms of Thermal Chemosensitization.- 4.3 Factors Which May Modify Thermal Chemosensitization.- 4.3.1 Heat-drug Sequence.- 4.3.2 Temperature.- 4.3.3 Heating Duration.- 4.3.4 Thermal Tolerance.- 4.3.5 Decreased pH and pO2.- 4.4 Therapeutic Index.- 4.5 Probable Thermal Sensitizing Agents.- 4.6 Future Directions for Preclinical Research.- 4.7 Clinical WBH Studies.- 5 Clinical and Biophysical Aspects of Systemic Hyperthermia.- 5.1 Thermal Regulation and WBH Methodologies.- 5.1.1 Review.- 5.1.2 WBH with a Regional Heat Boost.- 5.1.3 Electromagnetic Technology and WBH.- 5.1.4 Summary.- 5.2 Monitoring Body Site Temperature During WBH.- 5.3 Cardiorespiratory Effects of WBH.- 5.4 Biochemical Effects of WBH.- 5.5 Hematological Changes.- 5.6 Neurological Sequelae.- 5.7 Endocrine Function and WBH.- 5.8 Gastrointestinal Toxicity.- 5.9 Miscellaneous Toxicities.- 6 WBH Animal Studies.- 6.1 Introduction.- 6.2 Large Animals.- 6.3 Murine Models.- 6.4 Special Considerations.- 6.4.1 Species Differences.- 6.4.2 WBH and Metastatic Dissemination.- 7 Special Considerations for the Future.- 7.1 Nononcological Considerations.- 7.1.1 Collagen Vascular Diseases.- 7.1.2 Hypothermia.- 7.1.3 Acquired Immunodeficiency Syndrome.- 7.2 Implications of WBH Research for General Medical Practice.- 7.3 Systemic Hyperthermia: Summary Reflections Regarding Neoplastic Disease.- References.