Produktbild: Vertebrate Red Blood Cells
Band 28

Vertebrate Red Blood Cells Adaptations of Function to Respiratory Requirements

Aus der Reihe Zoophysiology

Fr. 137.00

inkl. gesetzl. MwSt., Versandkostenfrei


Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

08.12.2011

Verlag

Springer Berlin

Seitenzahl

262

Maße (L/B/H)

23.5/15.5/1.6 cm

Gewicht

423 g

Auflage

Softcover reprint of the original 1st ed. 1990

Sprache

Englisch

ISBN

978-3-642-83911-5

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

08.12.2011

Verlag

Springer Berlin

Seitenzahl

262

Maße (L/B/H)

23.5/15.5/1.6 cm

Gewicht

423 g

Auflage

Softcover reprint of the original 1st ed. 1990

Sprache

Englisch

ISBN

978-3-642-83911-5

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Vertebrate Red Blood Cells
  • 1. Introduction.- 2. Erythropoiesis and the Control of Circulating Red Cell Number.- 2.1 Erythropoietic Sites.- 2.2 Mammalian Erythropoiesis.- 2.3 Erythropoiesis in Nonmammalian Vertebrates.- 2.3.1 Fish.- 2.3.2 Amphibians.- 2.3.3 Reptiles.- 2.3.4 Birds.- 2.4 Senescence of Red Blood Cells.- 2.5 Erythropoiesis-Independent Factors Increasing Circulating Red Cell Number.- 3. The Biosynthesis and Structure of Haemoglobin.- 3.1 Uptake of Iron into Erythroid Cells.- 3.2 Haem Synthesis.- 3.3 Globin Synthesis.- 3.3.1 Structure of Globin Genes.- 3.3.2 Globin Chain Synthesis and Its Regulation.- 3.4 Subunit Assembly of Haemoglobin.- 3.5 Haemoglobin Structure in Vertebrates.- 3.5.1 Haemoglobin Heterogeneity in Adult Animals.- 3.5.2 Ontogenic Changes in Vertebrate Haemoglobins — Haemoglobin Switching.- 4. Structure of Circulating Red Cells.- 4.1 General Anatomy of the Cell.- 4.2 The Red Cell Membrane.- 4.2.1 Membrane Lipids.- 4.2.2 Structural and Membrane Proteins.- 5. Red Cells in Circulation: Factors Affecting Red Cell Shape and Deformability.- 5.1 Blood Viscosity.- 5.2 Deformability of Red Cells.- 5.2.1 Basic Principles.- 5.2.2 Methods for Measuring Red Cell Deformability.- 5.2.3 Deformation of Red Cells in Circulation.- 5.2.4 Factors Affecting Red Cell Deformability.- 6. Energy Metabolism and Regulation of Organic Phosphate Concentrations.- 6.1 Energy Consumption.- 6.2 Transport of Substrates into the Red Cells.- 6.2.1 Amino Acid Transport.- 6.2.2 Monosaccharide Transport.- 6.2.3 Transport of Nucleosides, Nucleic Acid Bases and Nucleotides.- 6.3 Glycolysis.- 6.4 Pentose Phosphate Pathway and Glutathione Metabolism.- 6.4.1 Pentose Phosphate Pathway.- 6.4.2 Glutathione Metabolism.- 6.5 Krebs Cycle and Oxidative Phosphorylation.- 6.6 Organic Phosphate Metabolism.- 6.6.1 Nucleotide Metabolism.- 6.6.2 Inositol Pentaphosphate Metabolism.- 6.7 Cellular Control of Red Cell Organic Phosphate Concentrations.- 6.7.1 Organic Phosphate Concentrations.- 6.7.2 Ontogenetic and Environmental Factors Influencing the Organic Phosphate Concentrations.- 7. Major Ion Transporting Pathways.- 7.1 Electrodiffusive Leak.- 7.2 Ion Channels.- 7.3 Anion Exchange.- 7.4 Ion Transport Coupled to Sodium or Potassium Gradient.- 7.4.1 Sodium/Potassium/Chloride Cotransport.- 7.4.2 Potassium/Chloride Cotransport.- 7.4.3 Alkali Metal/Proton Exchange.- 7.4.4 Sodium/Calcium Exchange.- 7.5 Active Transport.- 7.5.1 Sodium Pump.- 7.5.2 Calcium Pump.- 7.6 Membrane Potential.- 7.6.1 Gibbs-Donnan Equilibrium.- 7.6.2 Membrane Potential in the Presence of Active Transport.- 8. Control of Volume and pH.- 8.1 The Basic Model: Control of Red Cell pH and Volume in the Absence of Significant Secondarily Active Transport.- 8.1.1 Maintenance of the Steady-State Volume.- 8.1.2 Determinants of the Steady-State pH.- 8.1.3 pH and Volume Changes in Response to Carbon Dioxide Addition and Removal, and Acid and Base Loads.- 8.1.4 Volume Changes in Response to Osmotic Disturbances.- 8.2 Mammalian Red Cells.- 8.2.1 Human Red Cells.- 8.2.2 Ruminant Red Cells.- 8.2.3 Carnivore Red Cells.- 8.2.4 Rodent Red Cells.- 8.2.5 Lagomorpha Red Cells.- 8.3 Avian Red Cells.- 8.4 Reptilian Red Cells.- 8.5 Amphibian Red Cells.- 8.6 Fish Red Cells.- 8.6.1 Teleost Red Cells.- 8.6.2 Elasmobranch Red Cells.- 8.6.3 Agnathan Red Cells.- 9. Carbon Dioxide Transport.- 9.1 Distribution of Total Carbon Dioxide Content Between Red Cells and Plasma.- 9.2 Carbon Dioxide — Bicarbonate Equilibria.- 9.2.1 Uncatalyzed Interconversion Between Carbon Dioxide and Bicarbonate.- 9.2.2 Function of Carbonic Anhydrase.- 9.2.3 Role of Buffers.- 9.3 Formation of Carbamino Compounds.- 9.4 Mechanisms of Carbon Dioxide Excretion.- 10. Oxygen Transport.- 10.1 Haemoglobin-Oxygen Equilibria — Basic Principles.- 10.1.1 Oxygen Equilibrium Curve.- 10.1.2 Homotropic and Heterotropic Interactions.- 10.1.3 Effect of Haemoglobin Concentration.- 10.1.4 Temperature Effects.- 10.2 Methods for Determining Blood/Haemoglobin Oxygen Content and Oxygen Equilibrium Curves.- 10.2.1 Preparation of Blood or Haemoglobin Solutions for Determinations of Oxygen Equilibrium Curves.- 10.2.2 Methods for Determining Oxygen Equilibrium Curves.- 10.3 Molecular Aspects of Haemoglobin-Oxygen Binding.- 10.3.1 Binding of Oxygen to the Haem Group.- 10.3.2 Cooperativity.- 10.3.3 Bohr Effect.- 10.3.4 Binding of Organic Phosphates and Other Anions.- 10.4 Formation and Reduction of Methaemoglobin.- 10.5 Cellular and Molecular Adaptations of Haemoglobin Function to Variations in Respiratory Requirements.- 10.5.1 Ontogenetic Changes in Haemoglobin-Oxygen Affinity.- 10.5.2 Responses of Air-Breathers to High Altitude.- 10.5.3 Blood Oxygen Affinity in Burrowing Air-Breathers.- 10.5.4 Blood Oxygen Transport in Diving Animals.- 10.5.5 Red Cell Function in Hypoxic Water-Breathers.- 10.5.6 Blood Oxygen Affinity in Transition from Water-to Air-Breathing.- 10.5.7 Effects of Temperature on the Blood Oxygen Affinity in Poikilotherms.- 10.5.8 Blood Oxygen Transport in Relation to Activity and Physical Disturbances.- 10.5.9 Blood Oxygen Affinity in Hibernation, Aestivation and Torpor.- References.