Band 178
Membrane Defenses Against Attack by Complement and Perforins
Aus der Reihe
Current Topics in Microbiology and Immunology
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- Taschenbuch ausgewählt
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Sprache:Englisch
Fr. 137.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
16.12.2011
Herausgeber
Charles J. ParkerVerlag
Springer BerlinSeitenzahl
188
Maße (L/B/H)
23.5/15.5/1.2 cm
Gewicht
318 g
Auflage
Softcover reprint of the original 1st ed. 1992
Sprache
Englisch
ISBN
978-3-642-77016-6
In this volume a comprehensive review of membrane proteins
that regulate complement and perforin-mediated cytolysis is
presented. A detailed analysisis provided of the
biochemical, molecular, and functional features of these
proteins; the glycosyl phosphatidylinositol linked
proteins are covered, with emphasis placed on the functional
importance of this type of membrane anchor. Further chapters
include reviews of the effects of complement activation on
cells that are metabolically active, and of the regulation
of cell killing by cytotoxic lymphocytes, considering the
similarities and disparities between the complement and
perforin systems. The therapeutic use of recombinant CR1
for immune-mediated pathophysiological processes is
discussed in a separate section.
that regulate complement and perforin-mediated cytolysis is
presented. A detailed analysisis provided of the
biochemical, molecular, and functional features of these
proteins; the glycosyl phosphatidylinositol linked
proteins are covered, with emphasis placed on the functional
importance of this type of membrane anchor. Further chapters
include reviews of the effects of complement activation on
cells that are metabolically active, and of the regulation
of cell killing by cytotoxic lymphocytes, considering the
similarities and disparities between the complement and
perforin systems. The therapeutic use of recombinant CR1
for immune-mediated pathophysiological processes is
discussed in a separate section.
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