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  • Produktbild: Principles of Clinical Pharmacology
  • Produktbild: Principles of Clinical Pharmacology

Principles of Clinical Pharmacology 3rd Edition

Fr. 160.00

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.10.2012

Herausgeber

Arthur J. Atkinson + weitere

Verlag

Academic Press

Seitenzahl

652

Maße (L/B/H)

28.2/22.4/3.8 cm

Gewicht

1969 g

Auflage

3. Auflage

Sprache

Englisch

ISBN

978-0-12-385471-1

Beschreibung

Rezension

".this is an excellent textbook that provides a comprehensive overview of the fundamentals and state of the art of clinical pharmacology. It will be an invaluable reference source for many current and future scientists in the field." --Clinical Pharmacology and Therapeutics, June 2013

"Recent advances in pharmacogenetics, membrane transport, and biotechnology warrant a second edition of this excellent book...This will serve as an excellent text for an advanced course in principles of clinical pharmacology for graduate students, physicians, and PharmDs. Because of recent advances, the second edition is welcome. (4 Stars)" --Doody's

Zitat

".this is an excellent textbook that provides a comprehensive overview of the fundamentals and state of the art of clinical pharmacology. It will be an invaluable reference source for many current and future scientists in the field."--Clinical Pharmacology & Therapeutics, June 2013 "Recent advances in pharmacogenetics, membrane transport, and biotechnology warrant a second edition of this excellent book...This will serve as an excellent text for an advanced course in principles of clinical pharmacology for graduate students, physicians, and PharmDs. Because of recent advances, the second edition is welcome."--Thomas L. Pazdernik, PhD, University of Kansas Medical Center, FOR DOODY'S (4 Stars)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.10.2012

Herausgeber

Verlag

Academic Press

Seitenzahl

652

Maße (L/B/H)

28.2/22.4/3.8 cm

Gewicht

1969 g

Auflage

3. Auflage

Sprache

Englisch

ISBN

978-0-12-385471-1

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Principles of Clinical Pharmacology
  • Produktbild: Principles of Clinical Pharmacology

  • Chapter 1 Introduction

    PART 1: PHARMACOKINETICS:
    Chapter 2 Clinical pharmacokinetics
    Chapter 3 Compartmental analysis of drug distribution
    Chapter 4 Drug absorption and bioavailability
    Chapter 5 Effects of renal disease on pharmacokinetics
    Chapter 6 Kinetics of hemodialysis and hemofiltration
    Chapter 7 Effects of liver disease on pharmacokinetics
    Chapter 8 Noncompartmental vs. compartmental approaches to pharmacokinetic analysis
    Chapter 9 Distributed models of drug kinetics
    Chapter 10 Population pharmacokinetics

    PART 2: DRUG METABOLISM AND TRANSPORT:
    Chapter 11 Pathways of drug metabolism
    Chapter 12 Biochemical mechanisms of drug toxicity
    Chapter 13 Chemical assay of drugs and drug metabolites
    Chapter 14 Equilibrative and concentrative transport
    Chapter 15 Pharmacogenetics
    Chapter 16 Drug interactions

    PART 3: ASSESSMENT OF DRUG EFFECTS:
    Chapter 17 Physiological and laboratory markers of drug effect
    Chapter 18 Dose response and concentration response analysis
    Chapter 19 Kinetics of pharmacologic effect
    Chapter 20 Disease progression models

    PART 4: OPTIMIZING AND EVALUATING PATIENT THERAPY:
    Chapter 21 Sex differences in pharmacokinetics and pharmacodynamics
    Chapter 22 Drug therapy in pregnant and nursing women
    Chapter 23 Drug therapy in neonates and pediatric patients
    Chapter 24 Drug therapy in the elderly
    Chapter 25 Clinical analysis of adverse drug reactions
    Chapter 26 Quality assessment of drug therapy

    PART 5: DRUG DISCOVERY AND DEVELOPMENT:
    Chapter 27 Project management
    Chapter 28 Drug discovery
    Chapter 29 Pre-clinical development
    Chapter 30 Animal scale up
    Chapter 31 Phase I studies
    Chapter 32 PK and PD considerations in the development of biotechnology products and large molecules
    Chapter 33 Design of clinical development programs
    Chapter 34 Good design practices for clinical trials
    Chapter 35 Role of the FDA in guiding drug development
    Appendix I Table of Laplace Transforms
    Appendix II Answers to Study Problems