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  • Produktbild: Cortical Development
Band 39

Cortical Development From Specification to Differentiation

Fr. 192.00

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.07.2012

Herausgeber

Christine F. Hohmann

Verlag

Springer Berlin

Seitenzahl

181

Maße (L/B/H)

23.5/15.5/1.1 cm

Gewicht

306 g

Auflage

Softcover reprint of the original 1st ed. 2002

Sprache

Englisch

ISBN

978-3-642-53665-6

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.07.2012

Herausgeber

Christine F. Hohmann

Verlag

Springer Berlin

Seitenzahl

181

Maße (L/B/H)

23.5/15.5/1.1 cm

Gewicht

306 g

Auflage

Softcover reprint of the original 1st ed. 2002

Sprache

Englisch

ISBN

978-3-642-53665-6

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: Cortical Development
  • Produktbild: Cortical Development
  • Population Dynamics During Cell Proliferation and Neuronogenesis in the Developing Murine Neocortex.- References.- Mechanisms Regulating Lineage Diversity During Mammalian Cerebral Cortical Neurogenesis and Gliogenesis.- 1 Stem Cell Biology and Neural Development.- 2 Neural Lineage Elaboration and Bone Morphogenetic Proteins.- 3 Environmental and Transcriptional Regulation of Intermediate Progenitor Species.- 4 Mechanisms Regulating Neuronal and Astroglial Lineage Elaboration.- 5 Developmental Regulation and Lineage Potential of Radial Glia.- 6 Biology of Glial-Restricted Progenitors and the Generation of Oligodendrocytes.- 7 Role of ID Genes and Proteins in BMP-Mediated Cerebral Cortical Neural Fate Decisions.- 8 ID Genes and Proteins.- 8.1 Regulatory Roles.- 8.2 Nervous System Functions.- 9 Summary and Future Directions.- References.- Gap Junctions and Their Implications for Neurogenesis and Maturation of Synaptic Circuitry in the Developing Neocortex.- 1 Introduction.- 1.1 Survey of Neocortical Development.- 1.1.1 Neurogenesis, Migration and Development of Afferents.- 1.1.2 Development of Functional Synapses.- 2 Expression of Gap Junctions in the Neocortex.- 2.1 Expression During the Embryonic Development of the Neocortex.- 2.2 Expression During the Early Postnatal Development of the Neocortex.- 3 Modulation of Gap Junction Permeability During Early Postnatal Stages of Neocortical Development.- 4 Functional Implications of Gap Junctions in the Developing Neocortex.- 4.1 Neurogenesis.- 4.2 Development of Intrinsic Neuronal Properties.- 4.3 Domains, Calcium Oscillations and Circuit Formation.- 4.4 Electrical Coupling of Inhibitory Interneurons.- 5 Concluding Remarks.- References.- Influence of Radial Glia and Cajal-Retzius Cells in Neuronal Migration.- 1 Radial Glial Cells.- 2 Cajal-Retzius Cells and Reelin.- 3 MAM Model.- 4 What Prevents the Normal Laminar Pattern in E24 MAM-Treated Cortex?.- 5 Is There a Radialization Factor in Normal P) Cortex?.- 6 Summary and Conclusions.- References.- Neurotrophins and Cortical Development.- 1 Introduction.- 2 Distribution of the Neurotrophins and Their Receptors.- 2.1 Regulation of the Neurotrophins by Activity.- 2.2 Effects of Activity on Neurotrophin Secretion.- 3 Regulation of Synaptic Plasticity by the Neurotrophins.- 3.1 Acute Effects on Synaptic Function.- 3.2 Long-Term Potentiation and Depression.- 4 Neurotrophins and Structural Synaptic Plasticity.- 4.1 Axonal Growth.- 4.2 Dendritic Growth.- 4.3 Synapse Formation and Maintenance.- 4.4 Activity-Dependent Plasticity.- 5 Concluding Remarks.- References.- Role of Immediate Early Gene Expression in Cortical Morphogenesis and Plasticity.- 1 Neural Activity Plays a Critical Role in the Development of the Cerebral Cortex.- 2 Learning and Development Share Mechanisms of Neural Plasticity.- 3 Molecular Events Underlying Cortical Plasticity: the Immediate Early Gene Response.- 4 Effector Neuronal Immediate Early Genes.- 4.1 Growth Factors: Activin and BDNF.- 4.2 Extracellular Matrix and Signaling Molecules: Arcadlin, tPA, and Narp.- 4.3 Cytoskeletal Molecules: Arc.- 4.4 Signaling Molecules: Rheb and COX-2.- 4.5 Anchoring/Coupling Proteins: Homer.- 5 Conclusions.- References.- Role of Afferent Activity in the Development of Cortical Specification.- 1 Introduction.- 2 Sensory Modalities: Vision and Audition.- 2.1 Visual Processing.- 2.2 Auditory Processing.- 2.3 Vision Versus Audition.- 3 Intrinsic Determination of Modality-Specific Subregions of Cortex.- 4 A Role for Extrinsic Inputs in Specification of Local Cortical Networks.- 4.1 Theoretical Considerations for Experimentally Altering Cortical Inputs.- 4.2 The Rewiring Paradigm.- 4.3 Innervation of the Denervated MGN by the Retina.- 4.4 Physiological Consequences of Rewiring.- 4.5 Analyses of Rewired Al.- 4.5.1 Receptive Field Mapping.- 4.5.2 Optical Imaging of Intrinsic Signals.- 4.5.3 Local Connections Within Al.- 4.6 Other Signaling Mechanisms.- 4.7 Behavior and Effects Downstream of Primary Sensory Cortical Areas.- 4.8 Strategy to Identify and Characterize Cortical Genes Activated by Modality-Specific Inputs.- References.- Regional Forebrain Patterning and Neural Subtype Specification: Implications for Cerebral Cortical Functional Connectivity and the Pathogenesis of Neurodegenerative Diseases.- 1 Introduction.- 2 Role of the Ventral Telencephalon in Cerebral Cortical Development.- 3 Developmental Actions of Neurogenic bHLH Genes.- 4 Mechanisms Regulating the Transition from Neurogenesis to Gliogenesis.- 5 Olig Genes and Regional Shh Signaling.- 6 Importance of Regional Forebrain Patterning for Neural Subtype Specification.- 7 Role of Local BMP Signaling in Cerebral Cortical Neuronal and OL Lineage Elaboration.- 8 Generation of OL Lineage Species in the Adult Brain: Therapeutic Implications.- 9 Role of Gap Junction Channels and GABAergic Neuronal Subtypes in Cerebral Cortical Functional Connectivity.- 10 Regional Forebrain Patterning and Neurodegenerative Diseases.- 11 Summary and Future Directions.- References.