Band 49
Studying the electrotactic behavior of saos-2 cells in non-homogenous electric field strength
Aus der Reihe
Dresdner Beiträge zur Sensorik
-
- Deutsch, Englisch ausgewählt
Fr. 43.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
26.08.2013
Abbildungen
mit 9 Farbabbildungen
Verlag
TUDpressSeitenzahl
112
Maße (L/B/H)
22.5/15.8/0.8 cm
Gewicht
199 g
Auflage
1. Auflage
Sprache
Deutsch, Englisch
ISBN
978-3-944331-21-8
Electrotaxis is a biological phenomenon observed in several types of cells in which they respond to electric field strength and migrate towards one of the electrodes. As of now such behavior of cells has been only studied in homogenous electric fields where the electric field strength is constant. In this study the electrotaxis behavior of Saos-2 cells are studied in electric fields, where the electric field strength shows changeable gradients. A microfluidic device was designed with four electrodes to generate such non-homogenous electric fields. Experiments show that the cells migrated in the direction of the electric field lines when the electrical field strength exceeds a certain value. However, cells are not able to distinguish small variations in electric field strengths of less than 0.1 V/ mm. This allows the control of cell migration direction using such electric field gradients.
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