Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
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- Hardcover
- Taschenbuch ausgewählt
- eBook
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Sprache:Englisch
Fr. 192.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
26.01.2014
Herausgeber
Charles E. SamuelVerlag
Springer BerlinSeitenzahl
238
Maße (L/B/H)
23.5/15.5/1.4 cm
Gewicht
382 g
Auflage
2012
Sprache
Englisch
ISBN
978-3-642-42817-3
“The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins.”
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