Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs
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- Hardcover ausgewählt
- Taschenbuch
- eBook
-
Sprache:Englisch
Fr. 73.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
03.01.2017
Abbildungen
VII, 40 illus., 25 illus. in color., farbige Illustrationen, schwarz-weiss Illustrationen
Herausgeber
Tony K. L. Kiang + weitereVerlag
Springer SingaporeSeitenzahl
135
Maße (L/B/H)
24.1/16/1.4 cm
Gewicht
415 g
Auflage
1st edition 2016
Sprache
Englisch
ISBN
978-981-10-2112-1
Clinically-focussed, with easily accessible tables and chapter summaries suitable for clinicians and researchers, this comprehensive book provides a systematic, critical evaluation of the current literature. An updated clinical decision-making algorithm specifically tailored to the antiretroviral drugs is also provided. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. The clinical relevance of the interactions is systematically evaluated and gaps in literature discussed in the context of potential future experiments. In addition to the comprehensive summary of pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antiretroviral drugs on the market today (i.e. nucleotide reverse-transcriptase inhibitors, non-nucleoside reverse-transcriptase inhibitors, integrase inhibitors, and protease inhibitors), this book also provides detailed section summaries on theepidemiology of HIV infection, diagnosis and pharmacotherapy, basic pharmacology of the individual antiretrovirals, pertinent pre-clinical and in vitro molecular pharmacology, and in vitro drug interaction data available in the literature today.
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