Rapid acting fentanyl formulations in breakthrough pain in cancer.
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- Englisch ausgewählt
Fr. 62.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
18.12.2017
Verlag
Scholar's PressSeitenzahl
56
Maße (L/B/H)
22/15/0.4 cm
Gewicht
102 g
Auflage
1. Auflage
Sprache
Englisch
ISBN
978-620-2-30440-5
A rational and transparent method, System of Objectified Judgement Analysis (SOJA), for drug selection is described for selection of rapid acting fentanyl formulations for breakthrough pain in cancer-related pain. The relevant selection criteria for a group of drugs are defined and judged by a panel of experts. The more important that a selection criterion is considered, the higher the relative weight that is given to that criterion. The ideal properties for each selection criterion are determined and each drug is scored as a percentage of the relative weight for all selection criteria. Selection criteria (relative weight) were: number of available strengths (60), variability in rate of absorption (50), interactions (50), clinical efficacy (350), side-effects (150), ease of administration (140) and documentation (200). The sublingual fentanyl orally disintegrating tablet (Abstral) showed the highest overall score, followed by the nasal sprays (Instanyl and PecFent). These are the most attractive formulations from a formulary perspective.
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