Introduction: The Challenges and Opportunities of Blockchain Technologies by Benedetta Cappiello and Gherardo Carullo.- Part I – Understanding Blockchain: The Legal Perspective: Blockchain Based Organizations and the Governance of On-chain and Off-chain Rules: Towards Autonomous (Legal) Orders? by Benedetta Cappiello.- The Role of Blockchain in the Public Sector: An Overview by Gherardo Carullo.- Some Historical and Philosophical Remarks on the Rule of Law in the Time of Automation by Jean Lassègue.- Solving Cryptographic Puzzles: How to Mine? by Clemente Biondi Santi and Vincenzo Vespri.- Part II – Governance and Regulatory Issues: Cyberspace, Blockchain, Governance: How Technology Implies Normative Power and Regulation by Andrej Zwitter and Jilles Hazenberg.- Blockchain: The Regulatory Challenges for Central Banks and Financial Sector by Gino Giambelluca.- Blockchain-based Financial Investments and the Role of RegulatoryAuthorities: The Italian Perspective by Martina Tambucci.- Are VAT Rules Really Inadequate for Distributed Ledger Technology’s Transactions? by Michele Ferrari.- Blockchain and Comparative Law by Cristina Poncibò.- Part III – Smart Contracts and Dispute Resolution: Smart (Legal) Contracts, Or: Which (Contract) Law for Smart Contracts? by Giesela Rühl.- Smart (Legal) Contracts: Forum and Applicable Law Issues by Paolo Bertoli.- Integrating Smart Contracts with the Legacy Legal System: A US Perspective by Oliver R. Goodenough.- About Smart Contract Dispute Resolution by Amedeo Santosuosso.- Smart Contracts, ODR and the New Landscape of the Dispute Resolution Market by Pietro Ortolani.- Blockchain, Smart Contracts and New Certainties: What Future for Notaries? by Michele Nastri.- Part IV – The “Sustainable” Applications of Blockchain: Introduction to Distributed Ledger Technologies for Social, Development, and Humanitarian Impact by Giulio Coppi.- Blockchain, Earth Observation and Intelligent Data Systems: Implications and Opportunities for the Next Generation of Digital Services by Anna Burzykowska.- Justice for All: Jur’s Open Layer as a Case Study, Towards a More Open and Sustainable Approach by Alessandro Palombo and Raffaele Battaglini.- Blockchain and the GDPR: New Challenges for Privacy and Security by Marco Tullio Giordano.- Part V – Conclusions: Blockchain, Law and Governance: General Conclusion by Tony Lai.