1. What's in a name? nomenclature of essential tremor- syndrome or family of diseases?
Louis & Kuo
Is essential tremor a family of diseases or a syndrome? A family of diseases
Riboldi & Frucht
Is essential tremor a family of diseases or a syndrome? A syndrome
Pandey
2. Essential tremor- Is this an electrical or a degenerative disorder? Or is it both?
Louis & Kuo
Is essential tremor a degenerative disorder or an electric disorder? A degenerative disorder
Faust
Is essential tremor a degenerative disorder or an electric disorder? An electric disorder
Cho
3. How important is the inferior olive in essential tremor? An evolving story
Kuo & Louis
Is inferior olive central to the pathophysiology of essential tremor? Yes
Lang & Handforth
Is inferior olive central to the pathophysiology of essential tremor? No
Manto
4. Essential tremor as a harbinger- what is the cognitive fallout of having essential tremor?
Louis & Kuo
Does essential tremor increase the risk of dementia? Yes
Cosentino & Shih
Does essential tremor increase the risk of dementia? No
Rajput
5. Is essential tremor a disorder primarily due to GABA dysfunction?
Kuo & Louis
Is essential tremor a disorder of primary GABA dysfunction? Yes
Gironell
Is essential tremor a disorder of primary GABA dysfunction? No
Bellows &Jimenez-Shahed
6. The future of pharmacotherapies for essential tremor: enhancing GABA neurotransmission or reducing neuronal hyper-excitability?
Kuo & Louis
What is the next generation of medication for essential tremor? Enhancing GABAergic inhibition
Ondo
What is the next generation of medication for essential tremor? Reduction of hyper-excitability
Shukla