Synthesis and Bioactive studies of some new C-methylated flavonoids DE
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- Englisch ausgewählt
Fr. 111.00
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Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
10.06.2022
Verlag
LAP LAMBERT Academic PublishingSeitenzahl
220
Maße (L/B/H)
22/15/1.4 cm
Gewicht
346 g
Sprache
Englisch
ISBN
978-620-4-97761-4
These compounds possess an array of biological activities and are employed in the treatment of commonly occurring diseases. Literature survey revealed that chalcones, flavanones and aurones possess a broad spectrum of biological activities like antimicrobial, anti-inflammatory, antimalarial, antidepressant, antihistamine, antitubercular and anticancer. This thesis is an endeavor in this direction of synthesis and characterization of such compounds based on 1H NMR, 13CNMR, Mass spectroscopy and elemental analysis. One of the recently isolated flavanone (pisonivanone) from the Pisonia aculeate L was first time synthesized. In the present work a total 30 compounds including a series of 16 chalcones (3a-p) except 3e, 9 flavanones (4a-h&5) and 5 aurones (5a-e) were synthesized for the first time. Two new methods were developed for demethylation of the said flavonoids. Compound-3e and acetophenone-1 were synthesized by efficient alternative methods than earlier available approaches.
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