Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
26.09.2023
Herausgeber
Erica HelmerVerlag
American Medical PublishersSeitenzahl
244
Maße (L/B/H)
27.9/21.6/1.6 cm
Gewicht
862 g
Sprache
Englisch
EAN
9798887403755
Pharmacokinetics (PK) determines the outcome of substances which are administered in the human body and involves drug absorption, distribution, metabolism, and excretion (ADME) processes. Drug absorption is the movement of drug in the bloodstream from its site of administration. It depends on multiple factors, including the formulation and chemical properties of a drug, drug-food interactions and route of administration. Drug distribution is essential for determining drug efficacy and drug toxicity. Drug metabolism is the chemical alteration of the drug by the body. Genetics, age and drug interactions are some factors that affect drug metabolism. In clinical use, an enzyme named cytochrome P450 (CYP450) is responsible for the biotransformation or metabolism of all drugs. It is essential to comprehend the basic mechanisms governing the pharmacokinetics of a drug for designing personalized course of therapy for patients. This book provides comprehensive insights into the role of pharmacokinetics and metabolism in drug design. It is appropriate for students seeking detailed information in this area of study as well as for experts.
Kundinnen und Kunden meinen
Verfassen Sie die erste Bewertung zu diesem Artikel
Helfen Sie anderen Kund*innen durch Ihre Meinung