Histaminergic and Non-Histaminergic Itch: From Channels to Behavior
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Sprache:Englisch
Fr. 119.90
inkl. gesetzl. MwSt.Beschreibung
Produktdetails
Format
Kopierschutz
Ja
Family Sharing
Ja
Text-to-Speech
Nein
Erscheinungsdatum
11.07.2023
Herausgeber
Merab G. TsagareliVerlag
Nova Science Publishers, Inc.Seitenzahl
153 (Printausgabe)
Dateigröße
17361 KB
Sprache
Englisch
EAN
9798886978827
Itch (pruritus) is an unpleasant skin sensation that compels a person to scratch the affected area. The pathological consequences of itching affect the quality of life just as much as pain. Chronic pruritus conditions such as atopic dermatitis, allergic contact dermatitis, or psoriasis pose a significant socioeconomic burden. This book provides an original account of behavioral, cellular, and molecular aspects of itch in experimental rodents and human subjects. It concentrates on the role of different cellular membrane ion channels functioning in itch states and spinal and cortical pathways which mediate the neural cascade of itch-signaling. The book shows that ion channels are promising targets for developing a new group of antipruritic drugs at the periphery and central levels for therapeutic intervention.
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