This monograph emphasizes the importance of early detection and treatment of osteoarthritis, focusing on the role of Cartilage Oligomeric Matrix Protein (COMP) as a key biomarker in the early stages of the disease. The study explores the pathophysiological mechanisms linking COMP levels with cartilage degradation and joint inflammation. Special attention is given to modern diagnostic methods, including laboratory and imaging techniques, that enable the identification of osteoarthritis before irreversible structural damage occurs. The authors discuss preventive and therapeutic approaches aimed at slowing disease progression through early intervention. This work is intended for clinicians, researchers, and medical students seeking to enhance their understanding of molecular markers in osteoarthritis management.
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