Attractive for their flexibility, adaptive design methods represent a revolution in pharmaceutical research and development. Providing a unified and concise presentation of topics, "Theory and Application of Adaptive Design" emphasizes the relationship between different approaches and provides guidelines for each method. This book examines drug development as an integrated process, illustrating practical applications with step-by-step instructions. It also includes SAS code and R source code. The text also presents Bayesian approaches, which can be combined with adaptive design and trial simulation to form the ultimate statistical instrument for successful drug development programs.
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