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Produktbild: Essential Developmental Biology

Essential Developmental Biology

Fr. 138.00

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

16.11.2012

Abbildungen

col. Illustrations

Verlag

John Wiley & Sons Inc

Seitenzahl

496

Maße (L/B/H)

27.7/22.2/2 cm

Gewicht

1350 g

Auflage

3. Auflage

Sprache

Englisch

ISBN

978-0-470-92351-1

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

16.11.2012

Abbildungen

col. Illustrations

Verlag

John Wiley & Sons Inc

Seitenzahl

496

Maße (L/B/H)

27.7/22.2/2 cm

Gewicht

1350 g

Auflage

3. Auflage

Sprache

Englisch

ISBN

978-0-470-92351-1

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  • Produktbild: Essential Developmental Biology
  • Preface, ix

    About the companion website, xii

    Section N: Groundwork, 1

    N The excitement of developmental biology, 3

    Where the subject came from, 3

    Impact of developmental biology, 4

    Future impact, 4

    Further reading, 5

    O How development works, 7

    Ultrashort summary, 7

    Gametogenesis, 10

    Early development, 12

    Morphogenetic processes, 19

    Growth and death, 23

    Further reading, 25

    P Approaches to development: developmental genetics, 27

    Developmental mutants, 27

    Sex chromosomes, 29

    Maternal and zygotic, 29

    Genetic pathways, 29

    Genetic mosaics, 32

    Screening for mutants, 33

    Cloning of genes, 34

    Gain- and loss-of-function experiments, 34

    Gene duplication, 38

    Limitations of developmental genetics, 39

    Further reading, 40

    Q Approaches to development: experimental embryology, 42

    Normal development, 42

    Developmental commitment, 45

    Criteria for proof, 51

    Further reading, 52

    R Approaches to development: cell and molecular biology techniques, 54

    Microscopy, 54

    Study of gene expression by molecular biology methods, 58

    Study of gene expression by in situ methods, 61

    Microinjection, 65

    Cell-labeling methods, 66

    Further reading, 68

    Section O: Major model organisms, 71

    S Model organisms, 73

    The big six, 73

    Access and micromanipulation, 75

    Genetics and genome maps, 75

    Relevance and tempo, 76

    Other organisms, 76

    Further reading, 78

    T Xenopus, 80

    Oogenesis, maturation, and fertilization, 80

    Normal development, 82

    Experimental methods, 87

    Processes of regional specification, 92

    Inductive interactions, 95

    Further reading, 104

    U The zebrafish, 106

    Normal development, 106

    Genetics, 110

    Embryological and molecular techniques, 114

    Regional specification, 115

    Other uses for the zebrafish, 118

    Further reading, 120

    V The chick, 121

    Normal development, 122

    Regional specifi cation of the early embryo, 127

    Description of organogenesis in the chick, 133

    Further reading, 140

    NM The mouse, 141

    Mammalian fertilization, 141

    Normal development, 145

    Regional specifi cation, 153

    Human early development, 158

    Mouse developmental genetics, 159

    Other topics in mouse development, 164

    Further reading, 169

    NN Drosophila, 171

    Insects, 171

    Normal development, 173

    Drosophila developmental genetics, 178

    The developmental program, 181

    Further reading, 197

    NO Caenorhabditis elegans, 198

    Adult anatomy, 198

    Embryonic development, 200

    Analysis of postembryonic development, 208

    Further reading, 215

    Section 3: Organogenesis, 217

    NP Techniques for studying organogenesis and postnatal development, 219

    Genetics, 219

    Clonal analysis, 223

    Tissue and organ culture, 226

    Cell separation methods, 228

    Further reading, 230

    NQ Development of the nervous system, 231

    Overall structure and cell types, 231

    Anteroposterior patterning of the neural plate, 234

    Dorsoventral patterning of the neural tube, 238

    Neurogenesis and gliogenesis, 240

    The neural crest, 246

    Development of neuronal connectivity, 250

    Further reading, 257

    NR Development of mesodermal organs, 259

    Somitogenesis and myogenesis, 259

    The kidney, 266

    Germ cell and gonadal development, 269

    Limb development, 274

    Blood and blood vessels, 284

    The heart, 287

    Further reading, 293

    NS Development of endodermal organs, 296

    Normal development, 296

    Experimental analysis of endoderm development, 301

    The pancreas, 307

    Further reading, 312

    NT Drosophila imaginal discs, 314

    Metamorphosis, 314

    Disc development, 318

    Further reading, 328

    Section Q: Growth, regeneration, evolution, 331

    NU Tissue organization and stem cells, 333

    Types of tissue, 333

    Tissue renewal, 336

    Stem cells, 339

    Further reading, 360

    NV Growth, aging and cancer, 362

    Growth: control of size and proportion, 362

    Aging, 371

    Cancer, 374

    Further reading, 382

    OM Regeneration of missing parts, 384

    Distribution of regenerative capacity, 384

    Planarian regeneration, 385

    Insect limb regeneration, 388

    Vertebrate limb regeneration, 390

    General properties of regeneration, 399

    Further reading, 400

    ON Applications of pluripotent stem cells, 401

    Cell transplantation therapy, 401

    Embryonic stem cells, 403

    Personalized pluripotent stem cells, 406

    Proposed cell transplantation therapies using pluripotent stem cells, 411

    Further reading, 417

    OO Evolution and development, 419

    Macroevolution, 420

    The primordial animal, 424

    What really happened in evolution?, 429

    Further reading, 438

    Appendix: Key molecular components, 440

    Genes, 440

    Transcription factor families, 442

    Signaling systems, 443

    Inducing factor families, 445

    Cytoskeleton, 449

    Cell adhesion molecules, 451

    Extracellular matrix components, 452

    Further Reading, 452

    Glossary, 454

    Index, 467