Produktbild: Problem Solving in Enzyme Biocatalysis

Problem Solving in Enzyme Biocatalysis

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

08.01.2014

Verlag

John Wiley & Sons

Seitenzahl

344

Maße (L/B/H)

24.8/17.2/2.1 cm

Gewicht

678 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-34171-1

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

08.01.2014

Verlag

John Wiley & Sons

Seitenzahl

344

Maße (L/B/H)

24.8/17.2/2.1 cm

Gewicht

678 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-34171-1

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Problem Solving in Enzyme Biocatalysis
  • Preface ix
     
    Nomenclature xi
     
    Epsilon Software Information xxi
     
    1 Facts and Figures in Enzyme Biocatalysis 1
     
    1.1 Introduction 1
     
    1.2 Enzymes as Process Catalysts 3
     
    1.3 Evolution of Enzyme Biocatalysis: From Hydrolysis to Synthesis 5
     
    1.4 The Enzyme Market: Figures and Outlook 6
     
    References 7
     
    2 Enzyme Kinetics in a Homogeneous System 11
     
    2.1 Introduction 11
     
    2.2 Theory of Enzyme Kinetics 14
     
    2.3 Single-Substrate Reactions 17
     
    2.4 Multiple-Substrate Reactions 19
     
    2.5 Multiple-Enzyme Reactions 21
     
    2.6 Determination of Kinetic Parameters 22
     
    2.7 Effects of Operational Variables on Enzyme Kinetics 24
     
    Solved Problems 29
     
    Supplementary Problems 72
     
    References 84
     
    3 Enzyme Kinetics in a Heterogeneous System 87
     
    3.1 Introduction 87
     
    3.2 Immobilization of Enzymes 87
     
    3.3 Mass-Transfer Limitations in Enzyme Catalysis 92
     
    3.4 Determination of Intrinsic Kinetic and Mass-Transfer Parameters 102
     
    Solved Problems 105
     
    Supplementary Problems 127
     
    References 138
     
    4 Enzyme Reactor Design and Operation under Ideal Conditions 141
     
    4.1 Modes of Operation and Reactor Configurations 141
     
    4.2 Definition of Ideal Conditions 142
     
    4.3 Strategy for Reactor Design and Performance Evaluation 143
     
    4.4 Mathematical Models for Enzyme Kinetics, Modes of Operation, and Reactor Configurations under Ideal Conditions 143
     
    Solved Problems 157
     
    Supplementary Problems 174
     
    References 179
     
    5 Enzyme Reactor Design and Operation under Mass-Transfer Limitations 181
     
    5.1 Sequential Batch and Continuously Operated Reactors with Immobilized Enzymes 182
     
    5.2 Mathematical Models for Enzyme Kinetics, Modes of Operation, and Reactor Configurations under Mass-Transfer Limitations 183
     
    Solved Problems 185
     
    Supplementary Problems 198
     
    6 Enzyme Reactor Design and Operation under Biocatalyst Inactivation 203
     
    6.1 Mechanistically Based Mathematical Models of Enzyme Inactivation 203
     
    6.2 Effect of Catalytic Modulators on Enzyme Inactivation 205
     
    6.3 Mathematical Models for Different Enzyme Kinetics, Modes of Operation, and Reactor Configurations under Biocatalyst Inactivation 206
     
    6.4 Mathematical Models for Enzyme Kinetics, Modes of Operation, and Reactor Configurations under Simultaneous Mass-Transfer Limitations and Enzyme Inactivation 212
     
    6.5 Strategies for Reactor Operation under Biocatalyst Inactivation 213
     
    Solved Problems 215
     
    Supplementary Problems 233
     
    References 240
     
    7 Optimization of Enzyme Reactor Operation 243
     
    7.1 Strategy for the Optimization of Enzyme Reactor Performance 244
     
    7.2 Mathematical Programming for Static Optimization 247
     
    7.3 Dynamic Programming 248
     
    7.4 Statistical Optimization by Surface Response Methodology 249
     
    Solved Problems 254
     
    Supplementary Problems 272
     
    References 275
     
    Appendix A Mathematical Methods 277
     
    A.1. Newton's Method 277
     
    A.2. Curve Fitting by Least Squares 280
     
    A.3. Solving Ordinary Differential Equations 296
     
    A.4. Numerical Methods for Solving Differential Equations 302
     
    References 310
     
    Index 311