Patel, D: Formulation and Evaluation of Pulsatile Release Ta
-
- Englisch ausgewählt
Fr. 74.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
10.06.2012
Verlag
LAP LAMBERT Academic PublishingSeitenzahl
132
Maße (L/B/H)
22/15/0.8 cm
Gewicht
215 g
Sprache
Englisch
ISBN
978-3-659-15149-1
The aim of present research work is to develop single pulse pulsatile release tablets that release Lornoxicam instantly after the lag time of about 5 hour which can be used for treatment of rheumatoid arthritis where symptoms are at their prime in the morning hours. Such a pulsatile release tablet of Lornoxicam taken at bed time and release the drug in early morning, thus enhance patient compliance. From various approaches erodible compression coating system is selected for the formulation of pulsatile release tablets, in which outer coating containing mixture of hydrophilic polymer (sodium alginate) and hydrophobic polymer (ethylcellulose). The release profile of compression coated tablet exhibited lag time followed by burst release, in which outer shell break into two halves.
Noch keine Bewertungen vorhanden
Verfassen Sie die erste Bewertung zu diesem Artikel
Helfen Sie anderen Kundinnen und Kunden durch Ihre Meinung.