Band 59
Medicinal Chemistry Approaches to Personalized Medicine
Aus der Reihe
Methods and Principles in Medicinal Chemistry
Fr. 172.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
27.12.2013
Abbildungen
12 Farbabb.
Herausgeber
Karen Lackey + weitereVerlag
Wiley-VCHSeitenzahl
408
Maße (L/B/H)
2.6/16.4/24.3 cm
Gewicht
1004 g
Sprache
Englisch
ISBN
978-3-527-33394-3
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of cancer treatment, other key emerging areas, such as neurosciences and inflammation, are also covered.With its careful balance of current and future approaches, this handbook is a prime knowledge source for every drug developer, and one that will remain up to date for some time to come.From the content:* Discovery of Predictive Biomarkers for Anticancer Drugs* Discovery and Development of Vemurafenib* Targeting Basal-Cell Carcinoma* G-Quadruplexes as Therapeutic Targets in Cancer* From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease* Therapeutic Potential of Kinases in Asthma* DNA Damage Repair Pathways and Synthetic Lethality* Medicinal Chemistry in the Context of the Human Genomeand many more
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