Fibrin Sealant in Operative Medicine Volume 1: Otorhinolaryngology
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Sprache:Englisch
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Verlag:Springer Berlin
- Springer Fr. 74.90
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Fr. 137.00
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Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
01.08.1986
Herausgeber
G. Schlag + weitereVerlag
Springer BerlinSeitenzahl
163
Maße (L/B/H)
24.4/17/1.1 cm
Gewicht
400 g
Auflage
Softcover reprint of the original 1st ed. 1986
Sprache
Englisch
ISBN
978-3-540-16734-1
Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage,' and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect of fibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts.
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