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  • Produktbild: Enzymology and Molecular Biology of Carbonyl Metabolism 7
  • Produktbild: Enzymology and Molecular Biology of Carbonyl Metabolism 7
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Enzymology and Molecular Biology of Carbonyl Metabolism 7

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

24.10.2012

Herausgeber

Henry Weiner + weitere

Verlag

Springer Us

Seitenzahl

555

Maße (L/B/H)

24.4/17/3.1 cm

Gewicht

981 g

Auflage

Softcover reprint of the original 1st ed. 1999

Sprache

Englisch

ISBN

978-1-4613-7146-5

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

24.10.2012

Herausgeber

Verlag

Springer Us

Seitenzahl

555

Maße (L/B/H)

24.4/17/3.1 cm

Gewicht

981 g

Auflage

Softcover reprint of the original 1st ed. 1999

Sprache

Englisch

ISBN

978-1-4613-7146-5

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: Enzymology and Molecular Biology of Carbonyl Metabolism 7
  • Produktbild: Enzymology and Molecular Biology of Carbonyl Metabolism 7
  • Aldehyde Dehydrogenasé.- 1. The Big Book of Aldehyde Dehydrogenase Sequences: An Overview of the Extended Family.- 2. Reaction-Chemistry-Directed Sequence Alignment of Aldehyde Dehydrogenases.- 3. Three-Dimensional Structure of Mitochondrial Aldehyde Dehydrogenase: Mechanistic Implications.- 4. A Structural Explanation for the Retinal Specificity of Class 1 ALDH Enzymes.- 5. Structure and Function of Betaine Aldehyde Dehydrogenase: An Enzyme within the Multienzyme Aldehyde Dehydrogenase System.- 6. Evaluation of the Roles of the Conserved Residues of Aldehyde Dehydrogenase.- 7. Aldehyde Dehydrogenase Catalytic Mechanism: A Proposal.- 8. Inhibition of Human Mitochondrial Aldehyde Dehydrogenase by Metabolites of Disulfiram and Structural Characterization of the Enzyme Adduct by HPLC-Tandem Mass Spectrometry.- 9. Mechanism of Inhibition of Rat Liver Class 2 ALDH by 4-Hydroxynonenal.- 10. Aldehyde Inhibitors of Aldehyde Dehydrogenases.- 11. Covalent Modification of Sheep Liver Cytosolic Aldehyde Dehydrogenase by the Oxidative Addition of Coloured Phenoxazine, Phenothiazine and Phenazine Derivatives.- 12. A Thioester Analogue of an Amino Acetylenic Aldehyde Is a Suicide Inhibitor of Aldehyde Dehydrogenase and an Inducer of Apoptosis in Mouse Lymphoid Cells Overexpressing the bcl2 Gene.- 13. Reaction between Sheep Liver Mitochondrial Aldehyde Dehydrogenase and a Chromogenic ‘Reporter Group’ Reagent.- 14. Activity of the Human Aldehyde Dehydrogenase 2 Promoter Is Influenced by the Balance between Activation by Hepatocyte Nuclear Factor 4 and Repression by Perosixome Proliferator Activated Receptor ?, Chicken Ovalbumin Upstream Promoter-Transcription Factor, and Apolipoprotein Regulatory Protein-1.- 15. a,?-Unsaturated Aldehydes Mediate Inducible Expression of Glutathione S-Transferase in Hepatoma Cells through Activation of the Antioxidant Response Element (ARE).- 16. Effect of Arachidonic Acid Alone or with Prooxidant on Aldehyde Dehydrogenases in Hepatoma Cells.- 17. Prepubertal Regulation of the Rat Dioxin-Inducible Aldehyde Dehydrogenase (ALDH3).- 18. Effects of Tamoxifen and Toremifene on ALDH1 and ALDH3 in Human Retinal Pigment Epithelial Cells and Rat Liver.- 19. Negative Regulation of Rat Hepatic Aldehyde Dehydrogenase 3 by Glucocorticoids.- 20. Modulation of Class 3 Aldehyde Dehydrogenase Gene Expression: An Eye Opening Experience.- 21. Susceptibility of Hepatoma Cells to Lipid Peroxidation and Adaptation of ALDH 3C Activity to Iron-Induced Oxidative Stress.- 22. The Lack of AHD4 Induction by TCDD in Corneal Cells May Involve Tissue-Specific Regulatory Proteins.- 23. Human Corneal and Lens Aldehyde Dehydrogenases: Localization and Function(s) of Ocular ALDH 1 and ALDH3 Isozymes.- 24. The Role of Retinoid Metabolism by Alcohol and Aldehyde Dehydrogenases in Differentiation of Cultured Neuronal Cells.- 25. Metabolism of Retinaldehyde by Human Liver and Kidney.- 26. The Hunt for a Retinal-Specific Aldehyde Dehydrogenase in Sheep Liver.- 27. Cardiac Metabolism of Enals.- 28. Oxidation of Ethanol to Acetaldehyde in Brain and the Possible Behavioral Consequences.- 29. Cloning and Expression of a cDNA Encoding a Constitutively Expressed Rat Liver Cytosolic Aldehyde Dehydrogenase.- 30. The Roles of Acetaldehyde Dehydrogenases in Saccharomyces Cerevisiae.- 31. Characterization of an Aldehyde Dehydrogenase Gene Fragment from Mung Bean (Vigna radiatd) Using the Polymerase Chain Reaction.- 32. Aldehyde Dehydrogenase Gene Superfamily: The 1998 Update.- Alcohol Dehydrogenase.- 33. Human Alcohol Dehydrogenase Family: Functional Classification, Ethanol/Retinol Metabolism, and Medical Implications.- 34. Dynamics in Alcohol Dehydrogenase Elucidated from Crystallographic Investigations.- 35. Studies on Variants of Alcohol Dehydrogenases and Its Domains.- 36. Uncompetitive Inhibitors of Alcohol Dehydrogenases.- 37. Tandem Mass Spectrometry of Alcohol Dehydrogenase and Related Biomolecules.- 38. Function of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Gene Families in Retinoid Signaling.- 39. Primary Role of Alcohol Dehydrogenase Pathway in Acute Ethanol-Induced Impairment of Protein Kinase C-Dependent Signaling System.- 40. Class II Alcohol Dehydrogenase: A Suggested Function in Aldehyde Reduction.- 41. Zinc Binding Characteristics of the Synthetic Peptide Corresponding to the Structural Zinc Site of Horse Liver Alcohol Dehydrogenase.- 42. Amphibian Alcohol Dehydrogenase: Purification and Characterization of Classes I and III from Rana perezi.- 43. Extracellular Acidification: A Novel Detection System for Ligand/Receptor Interactions: Demonstration with Bioactive Peptides and CHO or Pancreatic ? Cells, but of Possible Interest for Tracing Putative Receptors in Ethanol Metabolism.- Short and Medium Chain Dehydrogenase.- 44. Multiplicity and Complexity of SDR and MDR Enzymes.- 45. Regulatory Factors and Motifs in SDR Enzymes.- 46. Bioinformatics in Studies of SDR and MDR Enzymes.- 47. The Protective Role of 11 ?-Hydroxysteroid Dehydrogenase/Carbonyl Reductase against Tobacco-Smoke Related Lung Cancer.- 48. Structure-Function Relationships of 3 ?-Hydroxysteroid Dehydrogenases Involved in Bile Acid Metabolism.- 49. Cloning and Sequencing of a New Comamonas testosteroni Gene Encoding 3?-Hydroxysteroid Dehydrogenase/Carbonyl Reductase.- 50. Comparative Properties of Three Pteridine Reductases.- 51. Effect of Androgen Structures on the Inhibition of Metyraponeinreductase in Rat, Mouse, and Human Liver.- Reductases.- 52. Physiological Relevance of Aldehyde Reductase and Aldose Reductase Gene Expression.- 53. The Aldo-Keto Reductases and Their Role in Cancer.- 54. Structure-Function Studies of FR-1: A Growth Factor-Inducible Aldo-Keto Reductase.- 55. 4-Hydroxynonenal Metabolism by Aldo/Keto Reductase in Hepatoma Cells.- 56. Interconversion Pathways of Aldose Reductase Induced by Thiol Compounds.- 57. Aldo-Keto Reductases in Norepinephrine Metabolism.- 58. Rotamers of Tolrestat and Their Binding Mode to Aldose Reductase.- 59. Stereoselective High-Affinity Reduction of Ketonic Nortriptyline Metabolites and of Ketotifen by Aldo-Keto Reductases from Human Liver.- 60. Formation of Lens Aldose Reductase Mixed Disulfides with GSH by UV Irradiation and Its Proteolysis by Lens Calpain.- 61. Inhibition of Aldose Reductase by Gossypol and Gossypol-Related Compounds.- 62. Inhibition of Human Aldose and Aldehyde Reductases by Non-Steroidal Anti-Inflammatory Drugs.- 63. Regulation of Aldose Reductase by Aldehydes and Nitric Oxide.- 64. The Cytotoxicity of Methylglyoxal and 3-Deoxyglucosone Is Decreased in the Aldehyde Reductase Gene-Transfected Cells.- 65. Enzymes Metabolizing Aldehydes in HL-60 Human Leukemic Cells.- 66. Rat Carbonyl Reductase: How Many Genes?.- 67. Cytostatic Drug Resistance: Role of Phase-I Daunorubicin Metabolism in Cancer Cells.- 68. Expression of mRNAs for Dihydrodiol Dehydrogenase Isoforms in Human Tissues.- 69. Alterations in the Expression of Daunorubicin Phase-I Metabolising Enzymes in Different Carcinoma Cell Lines.