Preface; 1. The pretherapeutic history of botulinum toxin Frank J. Erbguth; 2. Botulinum toxin: history of clinical development Daniel Truong and Mark Hallett; 3. Pharmacology of botulinum neurotoxins Daniel Truong and Mark Hallett; 4. Immunological properties of botulinum neurotoxins Hans Bigalke, Dirk Dressler and Jürgen Frevert; 5. Treatment of cervical dystonia Daniel Truong, Karen Frei and Cynthia L. Comella; 6. Examination and treatment of complex cervical dystonia Gerhard Reichel; 7. Ultrasound guidance for botulinim toxin therapy: cervical dystonia Katharine E. Alter; 8. Treatment of blepharospasm Carlo Colosimo, Dorina Tiple and Alfredo Berardelli; 9. Botulinum toxin in oromandibular dystonia Roongroj Bhidayasiri, Francisco Cardoso and Daniel Truong; 10. Treatment of focal hand dystonia Barbara Illowsky Karp, Chandi Prasad Das, Daniel Truong and Mark Hallett; 11. Botulinum toxin therapy of laryngeal muscle hyperactivity syndromes Daniel Truong, Arno Olthoff and Rainer Laskawi; 12. The use of botulinum toxin in otorhinolaryngology Ranier Laskawi, Arno Olthoff and Oleg Olegovich Ivanov; 13. Treatment of hemifacial spasm Karen Frei; 14. Spasticity Mayank S. Pathak and Allison Brashear; 15. The use of botulinum toxin in spastic infantile cerebral palsy Ann Tilton and H. Kerr Graham; 16. The use of botulinum toxin in spasticity using ultrasound guidance Andrea Santamato, Franco Molteni and Pietro Fiore; 17. The use of botulinum toxin in tic disorders and essential hand and head tremor Joseph Jankovic; 18. Treatment of stiff-person syndrome with botulinum toxin Diana Richardson and Bahman Jabbari; 19. Botulinum toxin applications in ophthalmology Peter Roggenkamper and Allan Scott; 20. Cosmetic uses of botulinum toxins Joshua Spanogle, Christopher Zachary and Dee Anna Glaser; 21. Hyperhidrosis Henning Hamm and Markus K. Naumann; 22. Botulinum toxin-A treatment for ischemic digits and chronic pain Michael W. Neumeister and Kelli Webb; 23. Botulinum toxin in wound healing Holger G. Gassner; 24. Use of botulinum toxin in neuropathic pain Szu-Kuan Yang and Chaur-Jongh Hu; 25. The use of botulinum toxin in the management of headache disorders Stephen D. Silberstein; 26. The use of botulinum toxin in musculoskeletal pain and arthritis Jasvinder A. Singh; 27. Treatment of plantar fasciitis with botulinum neurotoxins Bahman Jabbari and Shivam Om Mittal; 28. Use of botulinum toxin in the treatment of low back pain José De Andrés and Gustavo Fabregat; 29. Use of botulinum toxin in the treatment of piriformis syndrome Loren M. Fishman and Sarah B. Schmidhofer; 30. Ultrasound guided botulinum toxin injections for thoracic outlet syndrome Katharine E. Alter; 31. Botulinum toxin in the gastrointestinal tract Vito Annese and Daniele Gui; 32. Botulinum toxin application in urological disorders Stefano Carda and Brigitte Schurch; Index.