Band 23
Genetic Engineering Principles and Methods
Aus der Reihe
Genetic Engineering: Principles and Methods
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- Hardcover
- Taschenbuch ausgewählt
- eBook
-
Sprache:Englisch
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Auflage:Softcover reprint of the original 1st ed. 2001
- Softcover reprint of the original 1st ed. 1983 Fr. 76.90
- 2006 Fr. 192.00
- Softcover reprint of the original 1st ed. 1981 Fr. 72.90
- Softcover reprint of the original 1st ed. 1988 Fr. 74.90
- Softcover reprint of the original 1st edition 2002 Fr. 138.00
- Softcover reprint of the original 1st ed. 1991 Fr. 72.90
- Softcover reprint of the original 1st ed. 2001 Fr. 138.00 ausgewählt
- Softcover reprint of the original 1st ed. 1990 Fr. 137.00
- Softcover reprint of the original 1st ed. 2000 Fr. 152.00
- Softcover reprint of the original 1st ed. 2004 Fr. 138.00
- Softcover reprint of the original 1st ed. 2003 Fr. 138.00
- Softcover reprint of the original 1st ed. 1992 Fr. 72.90
- Softcover reprint of the original 1st ed. 1999 Fr. 152.00
- 1982 Fr. 72.90
- Softcover reprint of the original 1st ed. 1997 Fr. 212.00
- Softcover reprint of the original 1st ed. 1979 Fr. 72.90
Fr. 138.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
23.03.2013
Herausgeber
Jane K. SetlowVerlag
Springer UsSeitenzahl
232
Maße (L/B/H)
23.5/15.5/1.4 cm
Gewicht
391 g
Auflage
Softcover reprint of the original 1st ed. 2001
Sprache
Englisch
ISBN
978-1-4757-8798-6
Over the past decade, our laboratory and others have been concerned with molecular archaeological studies aimed at revealing the origins and evolutionary histories of permeases (1). These studies have revealed that several different families, defined on the basis of sequence similarities, arose independently of each other, at different times in evolutionary history, following different routes. When complete microbial genomes first became available for analysis, we adapted p- existing software and designed new programs that allowed us quickly to identify probable transmembrane proteins, estimate their topologies and determine the likelihood that they function in transport (2). This work allowed us to expand previously-recognized families and to identify dozens of new families. All of this work then led us to attempt to design a rational but comprehensive classification system that would be applicable to the complete complement of transport systems found in all living organisms (3). The classification system that we have devised is based primarily on mode of transport and energy coupling mechanism, secondarily on molecular phylogeny, and lastly on the substrate specificities of the individual permeases (4).
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