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  • Produktbild: Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2
  • Produktbild: Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2

Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2

Fr. 194.00

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

06.02.2015

Herausgeber

Charles Rupprecht + weitere

Verlag

Academic Press

Seitenzahl

386

Maße (L/B/H)

23.8/15.6/2.2 cm

Gewicht

768 g

Sprache

Englisch

ISBN

978-0-12-801919-1

Beschreibung

Rezension

"...a great, up-to-date reference on laboratory protocols for rabies diagnosis, research, and prevention. It is a must if you work in this field. Score: 85 - 3 Stars" -- Doody's

Portrait

Professor Charles E. Rupprecht is the Director of Research at the Global Alliance for Rabies Control and is the previous Director of WHO Collaborating Center for Rabies Research. He has won numerous federal service awards including the National Center for Infectious Diseases Public Health Protection Research Award in 2005.

Professor Nagarajan Thirumeni is a professor in biotechnology and the manager of Indian Immunologics Ltd. as well as the general manager of research and development in the biologics division of E. Ltd, Hyderabad, India.

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

06.02.2015

Herausgeber

Verlag

Academic Press

Seitenzahl

386

Maße (L/B/H)

23.8/15.6/2.2 cm

Gewicht

768 g

Sprache

Englisch

ISBN

978-0-12-801919-1

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2
  • Produktbild: Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2

  • I. Foreword
    II. Introduction
    III. Rabies Diagnosis
    a) Demonstration of virus
    i) Electron microscopy
    ii) Virus isolation in animals, the mouse inoculation test (MIT)
    iii) Virus isolation in cell culture, the rapid tissue culture inoculation test (RTCIT)
    iv) Rat basophilic leukemia cell sensor
    b) Demonstration of viral subunits and antigens
    i) Purification of rabies viral subunits
    ii) Preparation of fluorescent antibody conjugate in rabbits
    iii) Preparation of fluorescent antibody conjugate in goats
    iv) DFA (postmortem)
    v) Skin biopsy
    vi) Immuno histochemistry
    c) Demonstration of viral nucleic acids
    i) Gel based PCR
    ii) In situ PCR
    d) Demonstration of viral antibodies
    1. Binding Assays
    i) ELISA - Traditional
    ii) IFA
    iii) Counter Immunoelectrophoresis
    2. Functional Assays
    i) Mouse neutralization test
    ii) RFFIT
    iii) FAVN
    e) Typing/differentiation of lyssaviruses
    i) Antigenic typing by MAbs

    IV. Rabies Biologics
    i) Rabies vaccines for humans or other animals
    1. Purified chick embryo cell vaccine
    2. Purified Vero Cell Rabies Vaccine
    3. In vivo NIH potency testing of rabies vaccines
    9. In vitro Potency testing of rabies vaccines
    ii) Rabies antibodies/fragments
    1. Production of polyclonal rabies immune globulin in humans
    2. Production of polyclonal antibodies in horses
    3. Production of polyclonal antibodies in birds
    4. Production of full length human monoclonal antibodies using transgenic mice

    V. Development of Anti-Viral Approaches

    VI. Appendix
    i. List of biologics recommended by WHO for human rabies prophylaxis