Band 76
Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)
Aus der Reihe
Subcellular Biochemistry
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- Hardcover ausgewählt
- Taschenbuch
- eBook
-
Sprache:Englisch
Fr. 242.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
07.08.2015
Abbildungen
XXII, 58 illus., 37 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen
Herausgeber
Caroline Fonta + weitereVerlag
Springer NetherlandSeitenzahl
395
Maße (L/B/H)
24.1/16/2.7 cm
Gewicht
813 g
Auflage
1st ed. 2015
Sprache
Englisch
ISBN
978-94-017-7196-2
Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer's disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.
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