Inflammatory Disorders
Aus der Reihe
Advances in Experimental Medicine and Biology
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- Hardcover
- Taschenbuch ausgewählt
- eBook
-
Sprache:Englisch
Fr. 138.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
23.08.2016
Abbildungen
X, 11 illus., schwarz-weiss Illustrationen
Herausgeber
Mieczyslaw PokorskiVerlag
SpringerSeitenzahl
67
Maße (L/B)
25.4/17.8 cm
Gewicht
176 g
Auflage
Softcover reprint of the original 1st ed. 2015
Sprache
Englisch
ISBN
978-3-319-36372-1
The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.
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