Heparin-mimetic Polysaccharides Investigation of sulfate-modified levan polysaccharides and their bioactivity
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- Englisch ausgewählt
Fr. 68.90
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
13.02.2017
Verlag
LAP LAMBERT Academic PublishingSeitenzahl
92
Maße (L/B/H)
22/15/0.7 cm
Gewicht
155 g
Sprache
Englisch
ISBN
978-3-659-89389-6
Though heparin is one of the oldest drugs currently in widespread clinical use for undesired blood clots, its side effects are diverse and call for development of novel approaches. One of these approaches is the use of polysaccharides that can mimic heparin. Chemical modifications of polysaccharides, such as phosphorylation, sulfation, oxidation, carboxylation, offer a chance to increase their biological activities. The aim of this research was to obtain sulfated derivatives with differing sulfation degrees of levan polysaccharides and to investigate their acceptability to be used as heparin-mimetic agents.
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