Progress in the Chemistry of Organic Natural Products 115
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- Hardcover ausgewählt
- Taschenbuch
- eBook
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Sprache:Englisch
Fr. 395.00
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Gebundene Ausgabe
Erscheinungsdatum
03.04.2021
Abbildungen
VII, 203 p. 144 illus., 42 illus. in color.
Herausgeber
A. Douglas Kinghorn + weitereVerlag
SpringerSeitenzahl
203
Maße (L/B/H)
24.1/16/1.8 cm
Gewicht
494 g
Auflage
21001 Auflage 1st edition 2021
Sprache
Englisch
ISBN
978-3-030-64852-7
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca
2+
ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
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