Cell Signaling, 2nd edition Principles and Mechanisms

1. Introduction to Cell Signaling. 2. Principles and Mechanisms of Protein Interactions. 3. Signaling Enzymes and Their Allosteric Regulation. 4. Role of Post-Translational Modifications in Signaling. 5. Subcellular Localization of Signaling Molecules. 6. Second Messengers: Small Signaling Mediators. 7. Membranes, Lipids, and Enzymes that Modify Them. 8. Information Transfer Across the Membrane. 9. Regulated Protein Degradation. 10. The Modular Architecture and Evolution of Signaling Proteins. 11. Information Processing by Signaling Devices in Networks. 12. Signaling and Disease. 13. Diversity of Signaling Across Phylogeny 14. How Cells Make Decisions. 15. Methods for Studying Signaling Proteins and Networks.