Produktbild: Amino Acids, Peptides and Proteins in Organic Chemistry
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Amino Acids, Peptides and Proteins in Organic Chemistry Volume 1 - Origins and Synthesis of Amino Acids

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

19.08.2009

Abbildungen

Tabellen, schwarz-weiss, schwarz-weiss Illustrationen

Herausgeber

Andrew B. Hughes

Verlag

Wiley-VCH

Seitenzahl

734

Maße (L/B/H)

24.8/18.2/4.3 cm

Gewicht

1494 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-3-527-32096-7

Beschreibung

Rezension

"The presentation of selected typical experimental procedures is very welcome ... .Provides concise information from the point of view of experts working in the fields, and critically selecting the important recent literature." ( ChemBioChem , March 2010)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

19.08.2009

Abbildungen

Tabellen, schwarz-weiss, schwarz-weiss Illustrationen

Herausgeber

Andrew B. Hughes

Verlag

Wiley-VCH

Seitenzahl

734

Maße (L/B/H)

24.8/18.2/4.3 cm

Gewicht

1494 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-3-527-32096-7

Herstelleradresse

Wiley-VCH GmbH
product_safety@wiley.com
Wiley-VCH GmbH, Boschstrasse 12, DE-69469 Weinheim

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Die Leseprobe wird geladen.
  • Produktbild: Amino Acids, Peptides and Proteins in Organic Chemistry
  • PART I: Origins of Amino Acids

    EXTRATERRESTRIAL AMINO ACIDS
    Introduction
    ISM
    Comets
    Meteorites
    Micrometeorites and IDPs
    Mars
    Delivery of Extraterrestrial Amino Acid to the Earth and its Importance to the Origin of Life
    "TERRESTRIAL" AMINO ACIDS AND THEIR EVOLUTION
    Introduction
    What are the 20 "Terrestrial" Amino Acids?
    What do We Know about the Evolution of the Standard Amino Acid Alphabet?
    Amino Acids that Life Passed Over: A Role for Natural Selection?
    Why Does Life Genetically Encode L-Amino Acids?
    Summary, Synthesis, and Conclusions

    PART II: Production/Synthesis of Amino Acids

    USE OF ENZYMES IN THE SYNTHESIS OF AMINO ACIDS
    Introduction
    Chemo-Enzymatic Processes to Enantiomerically Pure Amino Acids
    Acylase Process
    Amidase Process
    Hydantoinase Process
    Ammonia Lyase Processes
    Aminotransferase Process
    AADH Process
    BETA-AMINO ACID BIOSYNTHESIS
    Introduction
    Biosynthesis of Beta-Amino Acids
    Conclusions and Future Prospects
    METHODS FOR THE CHEMICAL SYNTHESIS OF NONCODED ALPHA-AMINO ACIDS FOUND IN NATURAL PRODUCT PEPTIDES
    Introduction
    Noncoded CAAs
    Noncoded Amino Acids by Chemical Modification of Coded Amino Acids
    Noncoded Amino Acids with Elaborate Side-Chains
    SYNTHESIS OF N-ALKYL AMINO ACIDS
    Introduction
    N-Methylation via Alkylation
    N-Methylation via Schiff?s Base Reduction
    N-Methylation by Novel Methods
    N-Alkylation of Amino Acids
    RECENT DEVELOPMENTS IN THE SYNTHESIS OF BETA-AMINO ACIDS
    Introduction
    Synthesis of Beta-Amino Acids by Homologation of Alpha-Amino Acids
    Chiral Pool: Enantioselective Synthesis of Beta-Amino Acids from Aspartic Acid, Asparagine, and Derivatives
    Synthesis of Beta-Amino Acids by Conjugate Addition of Nitrogen Nucleophiles to Enones
    Synthesis of Beta-Amino Acids via 1,3-Dipolar Cycloaddition
    Synthesis of Beta-Amino Acids by Nucleophilic Additions
    Synthesis of Beta-Amino Acids by Diverse Addition or Substitution Reactions
    Synthesis of Beta-Amino Acids by Stereoselective Hydrogenation of Prochiral 3-Aminoacrylates and Derivatives
    Synthesis of Beta-Amino Acids by Use of Chiral Auxiliaries: Stereoselective Alkylation
    Synthesis of Beta-Amino Acids via Radical Reactions
    Miscellaneous Methods for the Synthesis of Beta-Amino Acids
    Experimental Procedures
    SYNTHESIS OF CARBOCYCLIC BETA-AMINO ACIDS
    Introduction
    Synthesis of Carbocyclic Beta-Amino Acids
    Synthesis of Functionalized Carbocyclic Beta-Amino Acid Derivatives
    Enzymatic Routes to Carbocyclic Beta-Amino Acids
    Experimental Procedures
    SYNTHETIC APPROACHES TO ALPHA, BETA-DIAMINO ACIDS
    Introduction
    Construction of the Carbon Backbone
    Introduction of the Nitrogen Atoms in the Carbon Backbone
    Experimental Procedures
    SYNTHESIS OF HALOGENATED ALPHA-AMINO ACIDS
    Introduction
    Halogenated Amino Acids with a Hydrocarbon Side-Chain
    Halogenated Amino Acids with an Aromatic Side-Chain
    Halogenated Amino Acids with Heteroatoms in the Aliphatic Side-Chain
    SYNTHESIS OF ISOTOPICALLY LABELED ALPHA-AMINO ACIDS
    Introduction
    Enzyme-Catalyzed Methods
    Chiral Pool Approach
    Chemical Asymmetric Methods
    Experimental Procedures
    SYNTHESIS OF UNNATURAL/NONPROTEINOGENIC ALPHA-AMINO ACIDS
    Introduction
    Chemical Methods
    Enzymatic Methods
    Experimental Procedures
    SYNTHESIS OF GAMMA AND DELTA-AMINO ACIDS
    Introduction
    Gamma-Amino Acids
    Delta-Amino Acids
    SYNTHESIS OF GAMMA-AMINOBUTYRIC ACID ANALOG
    Introduction
    Alpha-Substituted Gamma-Amino Acids
    Beta-Substituted Gamma-Amino Acids
    Trisubstituted Gamma-Amino Acids
    Hydroxy-Gamma-Amino Acids
    Unsaturated Gamma-Amino Acids
    Cyclic Gamma-Amino Acids
    Experimental Procedures