Band 318
Neurobiology of Essential Fatty Acids
Aus der Reihe
Advances in Experimental Medicine and Biology
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- Hardcover
- Taschenbuch
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Form:Einzelkauf Download
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Sprache:Englisch
Fr. 62.90
inkl. gesetzl. MwSt.Beschreibung
Produktdetails
Format
Kopierschutz
Nein
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
06.12.2012
Herausgeber
Nicolas G. Bazan + weitereVerlag
Springer New YorkSeitenzahl
444 (Printausgabe)
Dateigröße
51636 KB
Sprache
Englisch
EAN
9781461534266
It is increasingly evident that polyunsaturated fatty acids (PUFA), which in the past were often believed to be mere components of cellular membranes of neural tissue, are actually major determinants of the functional properties of neural cells and are intimately involved in brain disease processes. The two families of PUF A, which are derived from the essential polyenes, linoleic (18:26) and a-linolenic (18:33) acids, constitute a major proportion (-30%) of the total fatty acids esterified to brain phospholipids. Each family is distributed in membranes in a highly specific manner with respect to brain region, cell type, and position within each of the phosphoglycerides. Unlike their behavior in other organs, the PUF A components of brain turn over slowly and are relatively resistant to dietary modification. Their unique distribution and stability suggest that they play an important role in determining the functional properties of neural cells. However, until recently very little was known regarding the precise nature of their involvement.
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