Gastrulation Movements, Patterns and Molecules
Aus der Reihe
Bodega Marine Laboratory Marine Science Series
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Form:Einzelkauf Download
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Sprache:Englisch
Fr. 125.90
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Produktdetails
Format
Kopierschutz
Nein
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
06.12.2012
Herausgeber
Ray Keller + weitereVerlag
Springer UsSeitenzahl
332 (Printausgabe)
Dateigröße
25073 KB
Sprache
Englisch
EAN
9781468460278
Gastrulation is a fundamental process of early embryonic development. It involves virtually every aspect of cell and developmental biology and results in the formation of fundamental structural elements around which a developing animal's body plan is organized. As such it is not only an important process, but also one that is complicated and not easily dissected into its component parts. To understand the mechanisms of gastrulation one must acknowledge that gastrulation is fundamentally a biomechanical process (that is, a problem of cells generating forces in a three dimensional array, patterned in space and time such that appropriate tissue movements are executed). Three intertwined questions emerge: what cell activities generate forces, how are these cell activities patterned in space and time, and how are the resulting forces harnessed in three dimensional domains? To address these issues it is important to define and characterize regional cell behaviors and to learn how they are patterned in the egg and/ or by subsequent cell and tissue interactions. At the biochemical level, what are the cellular and extracellular molecules that control cell behavior? Finally, how are specific patterns of cellular activity integrated to produce tissue behavior? The task of answering the above questions, an immense task in itself, is compounded by the fact that the morphogenetic movements of gastrulation and their underlying mechanisms vary between different organisms.
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